Priga 75 mg (Capsule)
Unit Price: ৳ 16.00 (30's pack: ৳ 480.00)
Medicine Details
Category | Details |
---|---|
Generic | Pregabalin |
Company | Monicopharma ltd |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site in central nervous system tissues
Dosage
- Maximum recommended dose of Pregabalin is 100 mg three times a day (300 mg/day) in patients with creatinine clearance of at least 60 ml/min
- Dosing should begin at 50 mg three times a day (150 mg/day)
- The dose may be increased to 300 mg/day within 1 week based on efficacy and tolerability
- Recommended dose of Pregabalin CR is 165 mg once daily, increased to 330 mg once daily within 1 week
- Recommended dose of Pregabalin for postherpetic neuralgia is 75 to 150 mg two times a day or 50 to 100 mg three times a day (150 to 300 mg/day)
Administration
- Oral route of administration
- Can be taken with or without food
- Pregabalin CR tablet should be administered after an evening meal
Drug interaction
- Unlikely to be involved in significant pharmacokinetic drug interactions
Contraindications
- Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Common side effects in adults are dizziness, somnolence, dry mouth, edema, blurred vision, weight gain, and thinking abnormal
- Common side effects in pediatric patients for the treatment of partial onset seizures are increased weight and increased appetite
Pregnancy & Lactation
- No adequate and well-controlled studies with pregabalin in pregnant women
- Small amounts of pregabalin have been detected in the milk of lactating women
- Breastfeeding is not recommended during treatment with pregabalin
Precautions & Warnings
- Angioedema can occur and may be associated with life threatening respiratory compromise requiring emergency treatment
- Should be discontinued immediately in cases of angioedema and hypersensitivity reactions
- Increase the risk of suicidal thoughts or behavior
- May cause respiratory depression when used with concomitant CNS depressants
- May cause dizziness and somnolence and impair patients ability to drive or operate machinery
- Caution should be exercised when coadministering with thiazolidinedione antidiabetic agents
Use in Special Populations
- Safety and effectiveness in pediatric patients have not been established for certain indications
- Safety and effectiveness in pediatric patients below the age of 1 month have not been established
Overdose Effects
- Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block
- No specific antidote
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
- Keep in a cool & dry place (below 30°C), protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
Common Questions
- What is Priga 75 mg Capsule?
- How long do I need to use Priga 75 mg Capsule before I see improvement in my condition?
- At what frequency do I need to use Priga 75 mg Capsule?
- Should I use Priga 75 mg Capsule empty stomach, before food or after food?
- What are the instructions for the storage and disposal of Priga 75 mg Capsule?
- Does Priga 75 mg Capsule work in the same way for each disease?
- How long do I need to take Priga 75 mg Capsule?
- Is it necessary to continue taking Priga 75 mg Capsule even if I feel fine?
- Can I take Diazepam and Priga 75 mg Capsule together?
- Can the use of Priga 75 mg Capsule cause weight gain?