Regab 75 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
Pregabalin is a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) and binds with high affinity to the alpha2-delta site in central nervous system tissues.
Dosage
- Maximum recommended dose of Pregabalin for diabetic peripheral neuropathy is 100 mg three times a day
- Recommended dose for postherpetic neuralgia is 75 to 150 mg two times a day or 50 to 100 mg three times a day
- Recommended dose for fibromyalgia is 300 to 450 mg/day
- Recommended dose range of Pregabalin for neuropathic pain associated with spinal cord injury is 150 to 600 mg/day
Administration
- Route of administration: oral
- Pregabalin CR tablet should be administered after an evening meal
- Should be swallowed whole and should not be split, crushed or chewed
Interaction
Regab is unlikely to be involved in significant pharmacokinetic drug interactions.
Contraindications
Pregabalin is contraindicated in patients with known hypersensitivity to Pregabalin or any of its components.
Side Effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Thinking abnormal (primarily difficulty with concentration/attention)
Pregnancy & Lactation
No adequate and well-controlled studies with pregabalin in pregnant women. Breastfeeding is not recommended during treatment with pregabalin.
Precautions & Warnings
- Angioedema can occur and may be associated with life threatening respiratory compromise
- Respiratory depression may occur when used with concomitant CNS depressants
- May cause dizziness and somnolence and impair patients' ability to drive or operate machinery
- Increased seizure frequency or other adverse reactions may occur if rapidly discontinued
Use in Special Populations
Safety and effectiveness in pediatric patients have not been established for certain uses
Overdose Effects
Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
Keep in a cool & dry place below 30°C, protected from light & moisture. Keep out of the reach of children.
Chemical Structure
- Molecular Formula: C8H17NO2
- Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-919-pregabalin-chemical-structure-dKjKzfuVRrNkwNMBalNK.svg
Common Questions
- What is Regab 75 mg Capsule?
- How long do I need to use Regab 75 mg Capsule before I see improvement in my condition?
- At what frequency do I need to use Regab 75 mg Capsule?
- Should I use Regab 75 mg Capsule empty stomach, before food or after food?
- What are the instructions for the storage and disposal of Regab 75 mg Capsule?
- Does Regab 75 mg Capsule work in the same way for each disease?
- How long do I need to take Regab 75 mg Capsule?
- Is it necessary to continue taking Regab 75 mg Capsule even if I feel fine?
- Can I take Diazepam and Regab 75 mg Capsule together?
- Can the use of Regab 75 mg Capsule cause weight gain?
- Quick Tips: Regab 75 mg Capsule should be taken as per the dose and duration prescribed by your doctor