Pegamax 50 mg (Capsule)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Pregabalin
Company Astra biopharmaceuticals ltd
Also available as
Pegamax 75 mg capsule

Title

  • Pegamax

Categories

  • Medicine
  • Neuropathic Pain Management
  • Anticonvulsant
  • Fibromyalgia Treatment

Description

Pegamax is a medication used for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, fibromyalgia, and as adjunctive therapy for the treatment of partial-onset seizures in both adults and pediatric patients.

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

  • Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
  • Binds with high affinity to the alpha2-delta site in central nervous system tissues

Dosage

  • Maximum recommended dose of Pregabalin is 100 mg three times a day (300 mg/day) for DPN in adults
  • Recommended dose of Pregabalin is 75 to 150 mg two times a day or 50 to 100 mg three times a day (150 to 300 mg/day) for PHN in adults
  • Recommended dose of Pregabalin is 300 to 450 mg/day for fibromyalgia in adults
  • Recommended dose range of Pregabalin is 150 to 600 mg/day for neuropathic pain associated with spinal cord injury in adults
  • Pregabalin CR tablet should be administered after an evening meal

Administration

  • Oral route of administration
  • Can be taken with or without food
  • Pregabalin CR tablet should be swallowed whole and should not be split, crushed or chewed

Interaction

  • Unlikely to be involved in significant pharmacokinetic drug interactions
  • Not applicable for drug interaction with food and others

Contraindications

  • Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Side effects

  • Common side effects in adults: dizziness, somnolence, dry mouth, edema, blurred vision, weight gain, and thinking abnormal
  • Common side effects in pediatric patients: increased weight and increased appetite for the treatment of partial onset seizures

Pregnancy and lactation

  • No adequate and well-controlled studies with pregabalin in pregnant women
  • Small amounts of pregabalin detected in the milk of lactating women
  • Breastfeeding not recommended during treatment with pregabalin

Precautions and warnings

  • Angioedema can occur and may be associated with life threatening respiratory compromise
  • Discontinue immediately in case of hypersensitivity reactions
  • Increase the risk of suicidal thoughts or behavior
  • May cause dizziness and somnolence and impair patients ability to drive or operate machinery
  • Withdraw gradually over a minimum of 1 week
  • May cause peripheral edema

Use in special populations

  • Safety and effectiveness not established for pediatric patients for certain indications
  • Safety and effectiveness of Pegamax extended-release tablet not established in pediatric patients

Overdose effects

  • Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block
  • No specific antidote
  • General supportive care indicated including monitoring of vital signs and observation of the clinical status of the patient

Therapeutic class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage conditions

  • Keep in a cool & dry place (below 30°C)
  • Protected from light & moisture
  • Keep out of the reach of children

Chemical structure

  • Molecular Formula: C8H17NO2

Commonly asked questions

  • What is Pegamax 50 mg Capsule?
  • How long do I need to use Pegamax 50 mg Capsule before I see improvement in my condition?
  • At what frequency do I need to use Pegamax 50 mg Capsule?
  • Should I use Pegamax 50 mg Capsule empty stomach, before food or after food?
  • What are the instructions for the storage and disposal of Pegamax 50 mg Capsule?
  • Does Pegamax 50 mg Capsule work in the same way for each disease?
  • How long do I need to take Pegamax 50 mg Capsule?
  • Is it necessary to continue taking Pegamax 50 mg Capsule even if I feel fine?
  • Can I take Diazepam and Pegamax 50 mg Capsule together?
  • Can the use of Pegamax 50 mg Capsule cause weight gain?
  • Quick Tips

Other attributes

  • Medication for management of various types of neuropathic pain
  • Should not be split, crushed, or chewed
  • Route of administration is oral
  • Does not bind directly to GABAA, GABAB, or benzodiazepine receptors
  • May be taken with or without food
  • Dosage should be individualized based on patient response and tolerability
  • Can be safely used with Diazepam
  • Caution should be exercised when coadministering with thiazolidinedione antidiabetic agents
  • Keep medication unreachable to children and pets
  • Unlikely to be involved in significant pharmacokinetic drug interactions

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