Encorate Chrono 200 mg (Tablet (Controlled Release))

Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00

Medicine Details

Indications

  • Treatment of epilepsy
  • Prophylaxis of febrile convulsion
  • Prophylaxis of post-traumatic epilepsy
  • Treatment of bipolar disorder
  • Prophylaxis of migraine

Composition

  • Sodium Valproate tablet - 200 mg
  • Sodium Valproate syrup - 200 mg per 5 ml
  • Sodium Valproate controlled release 200 tablet - 200 mg
  • Sodium Valproate controlled release 300 tablet - 300 mg
  • Sodium Valproate controlled release 500 tablet - 500 mg
  • Sodium Valproate injection - 500 mg in 5 ml

Pharmacology

  • Endowed with anti-epileptic activity
  • Increase brain levels of gamma-aminobutyric acid (GABA)

Dosage & Administration

  • Oral administration
  • Initial dosage for adults and children
  • Maintenance dosage for adults and children
  • Injection dosage for adults and children

Interaction

  • Non-specific inhibitor of drug metabolism
  • Significant interactions with Phenobarbital, Phenytoin, Warfarin, Aspirin

Contraindications

  • Hypersensitivity to the drug
  • Liver dysfunction
  • Pregnancy
  • Women of childbearing potential

Side Effects

  • Common: anorexia, nausea, vomiting
  • CNS effects: sedation, ataxia, tremor
  • Rare: rash, alopecia, stimulation of appetite
  • Hepatic function effects: elevation of liver enzymes, fulminate hepatitis, hepatic injury, acute pancreatitis, hyperammonemia

Pregnancy & Lactation

  • Crosses the placenta
  • Associated with neural tube defects in newborn
  • Excreted in breast milk

Precautions & Warnings

  • Monitor liver functions
  • Ensure no potential for bleeding before major surgery
  • Take care in renal impairment, pregnancy, and breast-feeding
  • Avoid sudden withdrawal of therapy

Therapeutic Class

  • Primary anti-epileptic drugs

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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