Encorate Chrono 200 mg (Tablet (Controlled Release))
Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00
Medicine Details
Category | Details |
---|---|
Generic | Sodium valproate |
Company | Sun pharmaceutical bangladesh ltd |
Also available as |
Indications
- Treatment of epilepsy
- Prophylaxis of febrile convulsion
- Prophylaxis of post-traumatic epilepsy
- Treatment of bipolar disorder
- Prophylaxis of migraine
Composition
- Sodium Valproate tablet - 200 mg
- Sodium Valproate syrup - 200 mg per 5 ml
- Sodium Valproate controlled release 200 tablet - 200 mg
- Sodium Valproate controlled release 300 tablet - 300 mg
- Sodium Valproate controlled release 500 tablet - 500 mg
- Sodium Valproate injection - 500 mg in 5 ml
Pharmacology
- Endowed with anti-epileptic activity
- Increase brain levels of gamma-aminobutyric acid (GABA)
Dosage & Administration
- Oral administration
- Initial dosage for adults and children
- Maintenance dosage for adults and children
- Injection dosage for adults and children
Interaction
- Non-specific inhibitor of drug metabolism
- Significant interactions with Phenobarbital, Phenytoin, Warfarin, Aspirin
Contraindications
- Hypersensitivity to the drug
- Liver dysfunction
- Pregnancy
- Women of childbearing potential
Side Effects
- Common: anorexia, nausea, vomiting
- CNS effects: sedation, ataxia, tremor
- Rare: rash, alopecia, stimulation of appetite
- Hepatic function effects: elevation of liver enzymes, fulminate hepatitis, hepatic injury, acute pancreatitis, hyperammonemia
Pregnancy & Lactation
- Crosses the placenta
- Associated with neural tube defects in newborn
- Excreted in breast milk
Precautions & Warnings
- Monitor liver functions
- Ensure no potential for bleeding before major surgery
- Take care in renal impairment, pregnancy, and breast-feeding
- Avoid sudden withdrawal of therapy
Therapeutic Class
- Primary anti-epileptic drugs
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children