Epilim Chrono 500 mg (Tablet (Controlled Release))

Unit Price: ৳ 12.04 (8 x 6: ৳ 577.92)
Strip Price: ৳ 72.24

Medicine Details

Category Details
Generic Sodium valproate
Company Synovia pharma plc
Also available as
Epilim 200 mg syrup Epilim chrono 200 mg tablet Epilim chrono 300 mg tablet

Indications

  • Treatment of all types of epilepsy
  • Prophylaxis of febrile convulsion
  • Prophylaxis of post-traumatic epilepsy
  • Treatment of bipolar disorder
  • Prophylaxis of migraine

Composition

  • Sodium Valproate tablet 200 mg
  • Sodium Valproate syrup 200 mg/5ml
  • Sodium Valproate controlled release 200 tablet 200 mg
  • Sodium Valproate controlled release 300 tablet 300 mg
  • Sodium Valproate controlled release 500 tablet 500 mg
  • Sodium Valproate injection 500 mg

Pharmacology

  • Anti-epileptic activity against various seizures
  • Increase brain levels of gamma-aminobutyric acid (GABA)

Dosage & Administration

  • Oral administration
  • Initial dosage for adults and children
  • Maintenance dosage for adults and children
  • Dosage for febrile convulsion
  • Dosage for bipolar disorder
  • Dosage for prophylaxis of migraine
  • Injection dosage for adults and children

Interaction

  • Inhibition of drug metabolism
  • Significant interaction with Phenobarbital, Phenytoin, Warfarin, Aspirin

Contraindications

  • Hypersensitivity to the drug
  • Liver dysfunction
  • Pregnancy
  • Women of childbearing potential

Side Effects

  • Anorexia
  • Nausea
  • Vomiting
  • Sedation
  • Ataxia
  • Tremor
  • Rash
  • Alopecia
  • Stimulation of appetite
  • Elevation of liver enzymes
  • Fulminate hepatitis
  • Acute pancreatitis
  • Hyperammonemia

Pregnancy & Lactation

  • Crosses the placenta
  • Associated with neural tube defects
  • Excreted in breast milk

Precautions & Warnings

  • Monitoring liver functions before and during therapy
  • Assuring no potential for bleeding before major surgery
  • Care in renal impairment
  • Management during pregnancy and breast-feeding
  • Urinary ketone test false interpretation

Therapeutic Class

  • Primary anti-epileptic drugs

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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