Valex 200 mg (Tablet)

Unit Price: ৳ 4.00 (6 x 10: ৳ 240.00)
Strip Price: ৳ 40.00

Medicine Details

Category Details
Generic Sodium valproate
Company Incepta pharmaceuticals ltd
Also available as
Valex 200 mg syrup Valex cr 200 mg tablet Valex cr 300 mg tablet Valex cr 500 mg tablet Valex 500 mg injection

Indications

  • Treatment of all types of epilepsy
  • Partial seizures
  • Absence seizures (petit mal)
  • Generalized tonic-clonic seizures (grand mal)
  • Myoclonic seizures
  • Atonic seizures
  • Prophylaxis of febrile convulsion
  • Prophylaxis of post-traumatic epilepsy
  • Treatment of bipolar disorder
  • Prophylaxis of migraine

Composition

  • Sodium Valproate tablet contains Sodium Valproate BP 200 mg
  • Sodium Valproate syrup contains Sodium Valproate BP 200 mg
  • Sodium Valproate controlled release 200 tablet contains Sodium Valproate 200 mg as Sodium Valproate BP 133.2 mg & Valproic acid BP 58 mg
  • Sodium Valproate controlled release 300 tablet contains Sodium Valproate 300 mg as Sodium Valproate BP 199.8 mg & Valproic acid BP 87 mg
  • Sodium Valproate controlled release 500 tablet contains Sodium Valproate 500 mg as Sodium Valproate BP 333 mg & Valproic acid BP 145 mg
  • Sodium Valproate injection contains Sodium Valproate BP eqv. to Valproic Acid 500 mg

Pharmacology

  • Anti-epileptic activity against various seizures
  • Increase brain levels of gamma-aminobutyric acid (GABA)

Dosage & Administration

  • Oral administration
  • Tablets may be given once or twice daily
  • Syrup should be given in divided doses
  • Initial dosage for adults and children
  • Maximum dosage for adults and children
  • Injection administration for adults and children

Interaction

  • Non-specific inhibitor of drug metabolism
  • Interacts with Phenobarbital, Phenytoin, Warfarin, Aspirin

Contraindications

  • Known hypersensitivity to the drug
  • Liver dysfunction
  • Restricted use during pregnancy
  • Restricted use in women of childbearing potential

Side Effects

  • Anorexia
  • Nausea and vomiting
  • Sedation
  • Ataxia
  • Tremor
  • Rash
  • Alopecia
  • Stimulation of appetite
  • Elevation of liver enzymes
  • Hepatic injury
  • Acute pancreatitis
  • Hyperammonemia

Pregnancy & Lactation

  • Crosses the placenta
  • Associated with neural tube defects in newborn
  • Excreted in breast milk

Precautions & Warnings

  • Monitoring of liver functions
  • Ensuring no potential for bleeding before major surgery
  • Care in renal impairment
  • Avoiding sudden withdrawal of therapy
  • Avoiding use during pregnancy and in women of childbearing potential

Therapeutic Class

  • Primary anti-epileptic drugs

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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