Valex 200 mg/5 ml (Syrup)

100 ml bottle: ৳ 100.00

Medicine Details

Category Details
Generic Sodium valproate
Company Incepta pharmaceuticals ltd
Also available as
Valex 200 mg tablet Valex cr 200 mg tablet Valex cr 300 mg tablet Valex cr 500 mg tablet Valex 500 mg injection

Indications

  • Treatment of all types of epilepsy
  • Treatment of bipolar disorder
  • Prophylaxis of migraine
  • Prophylaxis of febrile convulsion
  • Prophylaxis of post-traumatic epilepsy

Composition

  • Sodium Valproate BP 200 mg tablet
  • Sodium Valproate BP 200 mg syrup
  • Sodium Valproate controlled release 200 mg tablet
  • Sodium Valproate controlled release 300 mg tablet
  • Sodium Valproate controlled release 500 mg tablet
  • Sodium Valproate injection equivalent to 500 mg Valproic Acid

Mode of Action

  • Anti-epileptic activity against a variety of seizures
  • Increase brain levels of gamma-aminobutyric acid (GABA)

Dosage & Administration

  • Initial dosage for adults and children
  • Maximum dosage for adults and children
  • Dosage for febrile convulsion
  • Dosage for bipolar disorder
  • Maintenance dosage for bipolar disorder
  • Dosage for prophylaxis of migraine
  • Dosage for intravenous injection in adults
  • Dosage for intravenous injection in children

Interaction

  • Non-specific inhibitor of drug metabolism
  • Interacts with Phenobarbital
  • Interacts with Phenytoin
  • Interacts with Warfarin
  • Interacts with Aspirin

Contraindications

  • Known hypersensitivity to the drug
  • Liver dysfunction
  • Restricted during pregnancy
  • Restricted in women of childbearing potential

Side Effects

  • Anorexia
  • Nausea
  • Vomiting
  • Sedation
  • Ataxia
  • Tremor
  • Rash
  • Alopecia
  • Stimulation of appetite
  • Elevation of liver enzymes
  • Fulminate hepatitis
  • Acute pancreatitis
  • Hyperammonemia

Pregnancy & Lactation

  • Crosses the placenta
  • Associated with neural tube defects
  • Excreted in breast milk
  • No risk to the child when breast-fed

Precautions & Warnings

  • Monitor liver functions before and during therapy
  • Ensure no undue potential for bleeding
  • Take care in renal impairment
  • Avoid sudden withdrawal of therapy
  • Avoid use during pregnancy and in women of childbearing potential
  • Partially eliminated as a ketone metabolite in urine

Therapeutic Class

  • Primary anti-epileptic drugs

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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