Valoate 200 mg/5 ml (Syrup)
100 ml bottle: ৳ 100.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Sodium valproate |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Treatment of all types of epilepsy
- Prophylaxis of febrile convulsion
- Prophylaxis of post-traumatic epilepsy
- Treatment of bipolar disorder
- Prophylaxis of migraine
Composition
- Sodium Valproate tablet
- Sodium Valproate syrup
- Sodium Valproate controlled release 200 tablet
- Sodium Valproate controlled release 300 tablet
- Sodium Valproate controlled release 500 tablet
- Sodium Valproate injection
Mode of Action
- Endowed with anti-epileptic activity
- Increase brain levels of gamma-aminobutyric acid (GABA)
Dosage & Administration
- Tablets may be given once or twice daily
- Syrup should be given in divided doses
- Injection for adults: slow intravenous injection over 3-5 minutes
- Injection for children: direct slow intravenous injection or infusion
Interaction
- Non-specific inhibitor of drug metabolism
- Significant interactions with Phenobarbital, Phenytoin, Warfarin, Aspirin
Contraindications
- Known hypersensitivity to the drug
- Liver dysfunction
- Restricted use during pregnancy and in women of childbearing potential
Side Effects
- Anorexia
- Nausea
- Vomiting
- Sedation
- Ataxia
- Tremor
- Rash
- Alopecia
- Elevation of liver enzymes in plasma
- Hepatic injury
- Acute pancreatitis
- Hyperammonemia
Pregnancy & Lactation
- Crosses the placenta
- Associated with neural tube defects in newborn if exposed in the first trimester
- Excreted in breast milk
Precautions & Warnings
- Monitoring of liver functions before and during therapy
- No undue potential for bleeding before major surgery
- Care in renal impairment, pregnancy, breast-feeding, systemic lupus erythematosus
- Sudden withdrawal should be avoided
Therapeutic Class
- Primary anti-epileptic drugs
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children