Valex CR 300 mg (Tablet (Controlled Release))

Unit Price: ৳ 10.00 (5 x 10: ৳ 500.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Sodium valproate
Company Incepta pharmaceuticals ltd
Also available as
Valex 200 mg tablet Valex 200 mg syrup Valex cr 200 mg tablet Valex cr 500 mg tablet Valex 500 mg injection

Title

  • Valex CR Vaiproate

Categories

  • Medicine
  • Healthcare
  • Pharmaceuticals

Description

  • An oral medication for the treatment of epilepsy, bipolar disorder, and prophylaxis of migraine
  • Available in various forms: tablet, syrup, controlled release tablet, and injection
  • Contains Sodium Valproate as the active ingredient

Indications

  • Treatment of various types of epilepsy including partial, absence, generalized tonic-clonic, myoclonic, atonic, and mixed seizures
  • Prophylaxis of febrile convulsion and post-traumatic epilepsy
  • Treatment of bipolar disorder and prophylaxis of migraine

Composition

  • Enteric-coated tablets containing Sodium Valproate BP 200 mg
  • Syrup containing Sodium Valproate BP 200 mg per 5 ml
  • Controlled release tablets in 200 mg, 300 mg, and 500 mg strengths
  • Injectable solution containing Sodium Valproate BP equivalent to Valproic Acid 500 mg per 5 ml

Mode of Action

  • Endowed with anti-epileptic activity against a variety of seizures
  • Suggested mechanism of action related to increased brain levels of gamma-aminobutyric acid (GABA)

Dosage & Administration

  • Oral administration in divided doses for epilepsy, bipolar disorder, and prophylaxis of migraine
  • Initial adult dosage of 600 mg daily, increasing to a maximum of 2.5 g daily in divided doses for epilepsy
  • Intravenous injection for adults and children

Interaction

  • Acts as a non-specific inhibitor of drug metabolism
  • Significant interaction with drugs such as Phenobarbital, Phenytoin, Warfarin, and Aspirin

Contraindications

  • Contraindicated in patients with known hypersensitivity to the drug and liver dysfunction
  • Restricted use during pregnancy and in women of childbearing potential

Side Effects

  • Common side effects include anorexia, nausea, and vomiting
  • Effects on the CNS include sedation, ataxia, and tremor
  • Minimized side effects with the use of enteric-coated tablets

Pregnancy & Lactation

  • Crosses the placenta and associated with neural tube defects in newborns
  • Excreted in breast milk but likely causes no risk to the child

Precautions & Warnings

  • Monitor liver functions before and during therapy
  • Ensure no potential for bleeding before starting and before major surgery
  • Take caution in renal impairment, pregnancy, breast-feeding, and systemic lupus erythematosus
  • Avoid sudden withdrawal of therapy

Therapeutic Class

  • Primary anti-epileptic drugs

Storage Conditions

  • Do not store above 30°C
  • Keep away from light and out of the reach of children

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