Valex CR 500 mg (Tablet (Controlled Release))

Unit Price: ৳ 13.00 (3 x 10: ৳ 390.00)
Strip Price: ৳ 130.00

Medicine Details

Category Details
Generic Sodium valproate
Company Incepta pharmaceuticals ltd
Also available as
Valex 200 mg tablet Valex 200 mg syrup Valex cr 200 mg tablet Valex cr 300 mg tablet Valex 500 mg injection

Indications

  • Treatment of epilepsy
  • Treatment of bipolar disorder
  • Prophylaxis of migraine
  • Prophylaxis of febrile convulsion
  • Prophylaxis of post-traumatic epilepsy

Composition

  • Available in tablet form
  • Available in syrup form
  • Available in controlled release tablet form
  • Available in injection form
  • Different strengths for tablet and controlled release tablet

Pharmacology

  • Endowed with anti-epileptic activity
  • Mechanism related to increased brain levels of gamma-aminobutyric acid (GABA)

Dosage & Administration

  • Oral administration
  • Different dosage for adults and children
  • Slow intravenous injection for adults
  • Intravenous injection or infusion for children

Interaction

  • Non-specific inhibitor of drug metabolism
  • Significant interaction with Phenobarbital, Phenytoin, Warfarin, Aspirin

Contraindications

  • Known hypersensitivity to the drug
  • Liver dysfunction
  • Restricted use during pregnancy and in women of childbearing potential

Side Effects

  • Anorexia, nausea, vomiting
  • CNS effects: sedation, ataxia, tremor
  • Rash, alopecia, stimulation of appetite
  • Elevation of liver enzymes
  • Fulminate hepatitis (rare)
  • Hepatic injury in children and those on multiple antiepileptic agents

Pregnancy & Lactation

  • Crosses placenta
  • Associated with neural tube defects in newborn
  • Excreted in breast milk
  • No risk during breastfeeding

Precautions & Warnings

  • Monitoring of liver functions
  • Ensure no potential for bleeding before surgery
  • Take care in renal impairment, pregnancy, and breastfeeding
  • May lead to a false interpretation of urine ketone test
  • Avoid sudden withdrawal of therapy

Therapeutic Class

  • Primary anti-epileptic drugs

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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