Topirva 25 mg (Tablet)
Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Topiramate |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Title
Topirva
Categories
- Medicine
- Anti-epileptic Drugs
Description
Topirva is indicated for the treatment of epilepsy and prophylaxis of migraine headache in adults and children. It exerts pharmacological actions on seizures and migraines through various mechanisms, including actions on voltage-dependent sodium channels, GABA receptors, and glutamate receptors.
Indications
- Epilepsy
- Generalized tonic-clonic seizures
- Partial seizures
- Lennox Gastaut Syndrome
- Migraine
- Prophylactic treatment
Pharmacology
- Voltage-dependent sodium channels actions
- GABA receptors stimulation
- Glutamate receptors inhibition
- Neuronal excitability blocking
Dosage & Administration
- Monotherapy for adults and children over 16 years
- Monotherapy for children aged 6-16 years
- Adjunctive therapy for adults and children over 16 years
- Adjunctive therapy for children aged 2-16 years
- Prophylaxis of migraine for adults and children over 16 years
Interactions
- Antiepileptic drugs interactions
- CNS Depressants caution
- Oral Contraceptives interaction
- Lithium pharmacokinetics
- Hydrochlorothiazide impact
- Metformin and Pioglitazone effects
- Glibenclamide monitoring
- Nephrolithiasis risk increase
Contraindications
- Hypersensitivity to any component
Side Effects
- Nausea
- Abdominal pain
- Dyspepsia
- Dry mouth
- Taste disturbance
- Dizziness
- Speech disorder
- Insomnia
- Impaired memory & concentration
- Depression
- Visual disturbance
- Suicidal ideation
- Metabolic acidosis
- Alopecia
- Leucopenia
- Thrombocytopenia
- Serious skin reaction
Pregnancy & Lactation
- Avoidance during pregnancy
- Avoidance during breastfeeding
Precautions & Warnings
- Gradual drug withdrawal
- Central nervous system-related adverse events
- Drowsiness and sedation
- Visual disturbances warning
- Restrictions on driving and operating machinery
Overdose Effects
- Severe metabolic acidosis risk
- Immediate stomach emptying recommendation
- Activated charcoal adsorption
- Supportive treatment necessity
- Haemodialysis effectiveness
Therapeutic Class
- Adjunct anti-epileptic drugs
Storage Conditions
- Temperature below 30°C
- Protection from light & moisture
- Keep out of the reach of children