Levopa 100 mg+10 mg (Tablet)

Unit Price: ৳ 4.01 (3 x 10: ৳ 120.30)
Strip Price: ৳ 40.10

Medicine Details

Category Details
Generic Levodopa carbidopa fc tablet
Company Acme laboratories ltd
Also available as
Levopa 250 mg tablet

Indications

  • Treatment of Parkinson's disease
  • Treatment of Parkinson's syndrome
  • Relief of parkinsonism symptoms
  • Relief of rigidity
  • Relief of bradykinesia
  • Management of tremor
  • Management of dysphagia
  • Management of sialorrhea
  • Management of postural instability

Description

  • Metabolic precursor of dopamine
  • Crosses the blood-brain barrier
  • Dopamine synthesis in the brain
  • Peripheral metabolism reduction

Dosage & Administration

  • Initiation dosage for 100/10 mg tablet
  • Titration upward for dosage optimization
  • Initial dose for 250/25 mg tablet
  • Maintenance dose individualization
  • Substitution of 250/25 mg tablet
  • Maximum daily dosage

Interaction

  • Postural hypotension interaction
  • Antihypertensive medicine adjustment
  • Concomitant use with tricyclic antidepressants
  • Decrease in bioavailability with ferrous sulphate
  • Therapeutic effects reduction with dopamine-2 receptor antagonists
  • Therapeutic effects reduction with isoniazid
  • Loss of therapeutic response observation

Contraindications

  • Hypersensitivity to Carbidopa
  • Hypersensitivity to Levodopa
  • Narrow-angle glaucoma
  • Potential activation of malignant melanoma

Side Effects

  • Central neuropharmacologic activity reactions
  • Diminishable adverse effects
  • Common adverse effects
  • Adverse effects in various body systems

Pregnancy & Lactation

  • Effects on human pregnancy unknown
  • Visceral and skeletal malformations in rabbits
  • Consideration of benefits vs. hazards in women of childbearing potential
  • Excretion in human milk unknown

Precautions & Warnings

  • Not recommended for medicine-induced extrapyramidal reactions
  • Usage in patients already taking Levodopa alone
  • Observation for depression and suicidal tendencies
  • Treatment caution for patients with psychoses
  • Administered cautiously to patients with specific diseases
  • Monitoring cardiac function in specific patients

Use in Special Populations

  • Safety and effectiveness in children not established
  • Not recommended for patients below 18 years

Therapeutic Class

  • Antiparkinson drugs

Storage Conditions

  • Cool and dry place
  • Protection from light

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