Cyclid 10 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 30.00

Medicine Details

Category Details
Generic Procyclidine hydrochloride
Company Incepta pharmaceuticals ltd
Also available as
Cyclid 5 mg tablet

Indications

  • Adjunctive treatment of all forms of parkinsonian syndrome
  • Symptomatic treatment of idiopathic, postencephalitic, and arteriosclerotic parkinsonian
  • Control of extrapyramidal symptoms induced by neuroleptic drugs

Pharmacology

  • Antimuscarinic antiparkinsonian agent
  • Corrects relative cholinergic excess in parkinsonian
  • Rapid absorption from gastrointestinal tract
  • Duration of effect up to 4 hours

Dosage & Administration

  • Oral administration after meals
  • Initial dosage for parkinsonism: 2.5 mg 3 times a day
  • Initial dosage for drug-induced extrapyramidal symptom: 2.5 mg 3 times a day
  • Maximum daily IM or IV injection: 20 mg

Interaction

  • Increased anticholinergic activity with agents having anticholinergic amantadine
  • Reduced absorption of ketoconazole by concomitant administration of procyclidine

Contraindications

  • Caution in children and geriatric patients
  • Cautious use in patients with diarrhea, cardiovascular disease, glaucoma, urinary retention, hepatic or renal impairment
  • Unestablished safety during pregnancy and lactation

Side Effects

  • Dryness of the mouth at usual dosage levels
  • Occasional adverse effects: mydriasis, blurred vision, G.I. effects, allergic reaction, muscular weakness
  • High doses may cause vertigo, confusion, and hallucination

Pregnancy & Lactation

  • Safe use requires weighing potential benefits against possible hazards to the mother and child

Precautions & Warnings

  • Precaution needed in case of hepatic and renal impairment
  • Caution in children, elderly, pregnancy, and lactation
  • Avoid abrupt withdrawal to prevent rebound Parkinsonism symptoms

Use in Special Populations

  • Unestablished safety and efficacy in the pediatric age group

Therapeutic Class

  • Antiparkinson drugs

Storage Conditions

  • Protect from light and moisture
  • Store below 25°C
  • Keep out of the reach of children

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