Dementa 5 mg (Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)

Strip Price: ৳ 100.00

Medicine Details

Category	Details
Generic	Memantine hydrochloride
Company	Ziska pharmaceuticals ltd
Also available as	Dementa xr 7 mg capsule Dementa xr 14 mg capsule

Indications

Treatment of all forms of dementia of the Alzheimer's type
Indicated in other types of dementia

Pharmacology

NMDA receptor antagonist
Absorbed after oral administration
Excreted predominantly unchanged in the urine
Linear pharmacokinetics
Low plasma protein binding (45%)
Mean volume of distribution 9-11 L/kg
Hepatic metabolism

Dosage & Administration

Recommended maintenance dose for adults and older patients: 20 mg/day
Dosage titration guideline provided
Different dosages for renal impairment
Not recommended for children under 18 years

Interaction

Effects on L-dopa, dopaminergic agonists, and anticholinergics
Effects on barbiturates and neuroleptics
Modified effects of antispasmodic agents
Not to be used with certain drugs

Contraindications

Contraindicated in patients with known hypersensitivity to Memantine Hydrochloride or any excipients

Side Effects

Frequent side effects: hallucination, confusion, dizziness, headache, fatigue
Occasional side effects: anxiety, hypertonus, vomiting, bladder infections, increased sexual drive
Slight chance of increasing the probability of epileptic seizures

Pregnancy & Lactation

Pregnancy Category B
Use during pregnancy only if potential benefit justifies potential risk to the fetus
Caution during administration to a nursing mother

Precautions & Warnings

Caregiver instructions for administration and dose escalation
Kidney function monitoring for patients with kidney dysfunction
Seizure evaluation
No risk of carcinogenesis, mutagenesis and impairment of fertility observed
Impact on operating vehicles or machinery

Storage Conditions

Store in a cool and dry place
Protected from light
Keep out of reach of children

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