Remtin 5 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Memantine hydrochloride |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of all forms of dementia of the Alzheimer's type
- May be indicated in other types of dementia
Pharmacology
- Action as an uncompetitive NMDA receptor antagonist
- Well absorbed after oral administration
- Linear pharmacokinetics
- Excreted predominantly unchanged in the urine
- Terminal elimination half-life of 60-80 hours
Dosage & Administration
- Recommended maintenance dose of 20 mg/day for adults and older patients
- Upward titration with 5 mg per week over 3 weeks
- Missed dose guidance
- Dosage adjustment for renal impairment
- Not recommended for children under 18 years
Interaction
- Enhancement of effects of L-dopa and dopaminergic agonists
- Reduction of effects of barbiturates and neuroleptics
- Modification of effects of antispasmodic agents
- Not to be used with specified medications
Contraindications
- Hypersensitivity to Memantine Hydrochloride or any excipients used in the formulation
Side Effects
- Hallucination
- Confusion
- Dizziness
- Headache
- Fatigue
- Anxiety
- Hypertonus
- Vomiting
- Bladder infections
- Increased sexual drive
- Potential increase in probability of epileptic seizures
Pregnancy & Lactation
- Pregnancy Category B
- Use during pregnancy if potential benefit justifies the potential risk to the fetus
- Caution when administered to a nursing mother
Precautions & Warnings
- Instruction for administration and dose escalation
- Monitoring of kidney function in patients with kidney dysfunction
- Seizures occurrence
- No risk of carcinogenesis, mutagenesis, and impairment of fertility
- Alteration of reaction time affecting safe driving and operation of machinery
Storage Conditions
- Store in a cool and dry place
- Protected from light
- Keep out of reach of children