Exelon 3 mg (Capsule)
Unit Price: ৳ 51.00 (2 x 14: ৳ 1,428.00)
Strip Price: ৳ 714.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rivastigmine tartrate |
| Company | Novartis bangladesh ltd |
| Also available as |
Title
- Rivastigmine Capsule
Categories
- Medicine
- Alzheimer's Disease Treatment
- Parkinson's Disease Treatment
Description
- Symptomatic treatment of mild to moderately severe Alzheimer's dementia
- Symptomatic treatment of mild to moderately severe dementia in patients with Idiopathic Parkinson's disease
Dosage Instructions
- Initial dose: Rivastigmine 1.5 mg twice a day
- Dose titration: Rivastigmine 1.5 mg, 3 mg, 4.5 mg, and 6 mg twice a day based on tolerability
- Maintenance dose: 3 mg to 6 mg twice a day
- Re-initiation of therapy: 1.5 mg twice daily if interrupted for several days
- Rivastigmine transdermal patch: Dose ranges from 4.6 mg/24 hours to 13.3 mg/24 hours based on tolerability and disease severity
Administration
- Twice a day with morning and evening meals
Pharmacology
- Binds reversibly with and inactivates cholinesterase
- Prevents the hydrolysis of acetylcholine
- Increases concentration of acetylcholine at cholinergic synapses
Interaction
- Exaggerates effects of succinylcholine-type muscle relaxants during anesthesia
- Should not be given concomitantly with cholinomimetic substances
- No pharmacokinetic interaction observed with digoxin, warfarin, diazepam, or fluoxetine
Contraindications
- Hypersensitivity to the active substance or other carbamate derivatives
Side Effects
- Commonly reported gastrointestinal adverse reactions including nausea and vomiting
- Higher susceptibility in female patients
Pregnancy & Lactation
- Not recommended during pregnancy unless clearly necessary
- Excretion into milk
Precautions & Warnings
- Monitor body weight
- Caution in patients with respiratory diseases, urinary obstruction, seizures, renal impairment, mild to moderate hepatic impairment, asthma, or obstructive pulmonary disease
Use in Special Populations
- Increased exposure in moderate renal and mild to moderate hepatic impairment
- Not recommended for use in children
Overdose Effects
- Accidental overdose may result in symptoms such as nausea, vomiting, diarrhea, hypertension, hallucinations, bradycardia, and syncope
- Conservative management recommended in most cases
- Use of antiemetics and atropine in severe cases
Therapeutic Class
- Drugs for Dementia
Storage Conditions
- Store in a cool and dry place, protected from light