Demelon 1.5 mg (Capsule)

Unit Price: ৳ 23.00 (4 x 7: ৳ 644.00)
Strip Price: ৳ 161.00

Medicine Details

Category Details
Generic Rivastigmine tartrate
Company Unimed unihealth pharmaceuticals ltd
Also available as
Demelon 3 mg capsule

Product Title

  • Rivastigmine Capsule
  • Rivastigmine Transdermal Patch

Categories

  • Alzheimer's Dementia Medication
  • Parkinson's Disease Dementia Medication
  • Cholinesterase Inhibitor

Description

  • Symptoms Treated:
    • Mild to Moderately Severe Alzheimer's Dementia
    • Mild to Moderately Severe Dementia in Idiopathic Parkinson's Disease
  • Pharmacology: Carbamate derivative related to physostigmine, cholinesterase inactivation, brain acetylcholinesterase specificity
  • Dosage Form:
    • Capsule
    • Transdermal Patch
  • Dosage Instructions:
    • Capsule:
      • Initial Dose: 1.5 mg twice a day
      • Dose Titration: 1.5 mg to 6 mg twice a day based on tolerability
      • Maintenance Dose: 3 mg to 6 mg twice a day
      • Re-initiation of Therapy: Start at 1.5 mg twice daily
    • Transdermal Patch:
      • Initial Dose: 4.6 mg/24 hours
      • Dose Titration: 4.6 mg to 13.3 mg/24 hours based on tolerability
      • Specific Disease Doses:
        • Mild to Moderate Alzheimer's & Parkinson's Disease Dementia: 9.5 mg/24 hours or 13.3 mg/24 hours once daily
        • Severe Alzheimer's Disease: 13.3 mg/24 hours once daily
      • Treatment Interruption: Retitrate dosage starting at 4.6 mg per 24 hours
  • Administration: Twice a day, with morning and evening meals
  • Interactions:
    • Anaesthesia: Exaggerated effects on succinylcholine-type muscle relaxants
    • Other Medications:
      • Cholinomimetic Substances
      • Anticholinergic Medicinal Products
    • Pharmacokinetic Interaction: None observed with digoxin, warfarin, diazepam, or fluoxetine
    • Cardiac Conduction: No untoward effects observed with digoxin
  • Contraindications: Hypersensitivity to the active substance or other carbamate derivatives
  • Side Effects: Most commonly gastrointestinal, including nausea and vomiting
  • Pregnancy & Lactation: Not recommended during pregnancy or lactation
  • Precautions & Warnings:
    • Special Conditions:
      • Sick Sinus Syndrome
      • Conduction Defects
      • Respiratory Diseases
      • Renal Impairment
      • Mild to Moderate Hepatic Impairment
      • Asthma
      • Obstructive Pulmonary Disease
    • Monitoring: Body weight
  • Use in Special Populations:
    • Renal and Hepatic Impairment: Increased exposure in moderate renal and mild to moderate hepatic impairment
    • Use in Children: Not recommended
  • Overdose Effects: Nausea, vomiting, diarrhea, hypertension, hallucinations, bradycardia, or syncope
  • Therapeutic Class: Drugs for Dementia
  • Storage Conditions: Cool and dry place, protected from light

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