Dicon 5 mg (Tablet)
Unit Price: ৳ 0.28 (10 x 10: ৳ 28.00)
Strip Price: ৳ 2.80
Medicine Details
| Category | Details |
|---|---|
| Generic | Glibenclamide |
| Company | Jayson pharmaceuticals ltd |
Indications
- Treatment of non insulin dependent diabetes melitus (NIDDM)
- Ineffective in completely pancreatectomized patients
Pharmacology
- Reduces blood sugar concentration by stimulating secretion of endogenous insulin
- Reduces basal hepatic glucose production
- Enhances peripheral insulin action at target sites
Dosage & Administration
- Initial stabilization dosage: Glibenclamide half tablet (2.5 mg) taken initially during or immediately after breakfast
- Changeover from insulin to Glibenclamide possible for mildly diabetic patient with fewer than 20 units daily insulin requirement
- Daily doses in excess of 10 mg may be taken in 2 divided doses
Interaction
- Alcohol, cyclophosphamide, monoamino oxidase inhibitors, and certain long-acting sulphonamides may enhance the hypoglycemic effect of Dicon
Contraindications
- Severe metabolic de-compensation with acidosis
- Pregnancy
- Diabetes mellitus complicated by fever, trauma or gangrene
Side Effects
- Nausea
- Vomiting
- Epigastric pain
- Dizziness
- Headache
- Allergic skin reactions
- Haemopoietic reactions like leukopenia and thrombocytopenia
Pregnancy & Lactation
- No information on the use of Glibenclamide in human pregnancy
- Animal studies show no hazard
Precautions & Warnings
- Weight reduction is of the greatest importance in the treatment of diabetes
Overdose Effects
- Symptoms: Hypoglycaemia
- Management: Mild hypoglycaemic symptoms without loss of consciousness may be treated with oral glucose and adjust drug dosage and/or meal patterns
Therapeutic Class
- Sulfonylureas
Storage Conditions
- Should be stored in a dry place below 30˚ C