Adglim 1 mg (Tablet)

Product Title

• Adglim Tablets

Category

• Medicine
• Diabetes Management
• Pharmaceutical

Description

• Adglim is indicated as an adjunct to diet and exercise to lower the blood glucose in patients with noninsulin dependent (Type II) diabetes mellitus (NIDDM)
• Glimepiride is a sulfonylurea antidiabetic agent which decreases blood glucose concentration
• In principle, the dosage of Glimepiride is governed by the desired blood sugar level
• Glimepiride tablet must be swallowed with sufficient amount of liquid
• Hypoglycaemia, temporary visual impairment, nausea, vomiting, diarrhoea, abdominal pain, urticaria, fall in blood pressure

Indications

• Adjunct to diet and exercise
• Lower blood glucose in Type II diabetes mellitus
• Used concomitantly with metformin
• Use in combination with insulin to lower blood glucose

Pharmacology

• Stimulates insulin release from pancreatic beta cells
• Improves sensitivity of beta cells to glucose stimulus
• Reduces basal hepatic glucose production
• Increases peripheral tissue sensitivity to insulin

Dosage

• Initial dose of 1 mg once daily
• Gradual dose titration based on regular blood sugar monitoring
• Usual dose range is 1 to 4 mg daily
• Timing and distribution of doses decided by physician

Administration

• Tablets must be swallowed with sufficient liquid

Interaction

• Potential interactions with ACE inhibitors, aminosalicylic acid, anabolic steroids, azapropazone, coumarin derivatives
• Other drugs may attenuate the hypoglycaemic action of Adglim

Contraindications

• Not suitable for insulin-dependent diabetes mellitus
• Not for the treatment of diabetic ketoacidosis or diabetic coma
• Hypersensitivity to Glimepiride or other sulfonylureas

Side Effects

• Hypoglycaemia
• Temporary visual impairment
• Nausea
• Vomiting
• Diarrhoea
• Abdominal pain
• Urticaria
• Fall in blood pressure

Pregnancy & Lactation

• Not to be taken during pregnancy
• Must not be taken by breastfeeding women

Precautions & Warnings

• Initial weeks may increase risk of hypoglycaemia
• Careful monitoring required
• Promptly controlled by immediate intake of carbohydrates

Overdose Effects

• Hypoglycaemia
• Treatment with oral glucose
• Severe cases constitute medical emergencies

Therapeutic Class

• Sulfonylureas

Storage Conditions

• Do not store above 30°C
• Keep away from light and out of the reach of children

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