Amaryl 3 mg (Tablet)

Unit Price: ৳ 16.55 (2 x 15: ৳ 496.50)
Strip Price: ৳ 248.25

Medicine Details

Title & Categories

  • Amaryl Tablet
  • Antidiabetic Agent
  • Sulfonylureas

Primary Function

Lowers blood glucose levels in noninsulin dependent (Type II) diabetes mellitus (NIDDM) patients

Indications

  • Adjunct to diet and exercise for NIDDM patients
  • May be used concomitantly with metformin
  • Combination with insulin for inadequate glycaemic control by diet and exercise

Mechanism of Action

Stimulates release of insulin from pancreatic beta cells, improves sensitivity to glucose stimulus, reduces hepatic glucose production, increases peripheral tissue sensitivity to insulin

Dosage Range

1mg-6mg once daily, based on blood sugar monitoring

Administration

Swallow whole with sufficient liquid

Interaction

  • Potentiates Hypoglycaemic Action:
    • ACE inhibitors
    • Anabolic steroids
    • Chloramphenicol
    • Fluoxetine
  • Attenuates Hypoglycaemic Action:
    • Barbiturates
    • Calcium channel blockers
    • Corticosteroids

Contraindications

  • Insulin dependent (Type I) diabetes mellitus
  • Diabetic ketoacidosis
  • Hypersensitivity to Glimepiride
  • Severe hepatic or renal dysfunction

Side Effects

  • Hypoglycaemia
  • Temporary visual impairment
  • Nausea
  • Vomiting
  • Diarrhoea
  • Urticaria

Pregnancy & Lactation

  • Not to be taken during pregnancy, changeover to insulin required
  • Must not be taken by breastfeeding women

Precautions & Warnings

  • Increased risk of hypoglycaemia in initial weeks of treatment
  • Prompt control with immediate intake of carbohydrates

Overdose Effects

  • Hypoglycaemia
  • Severe hypoglycaemic reactions with coma or seizure

Therapeutic Class

Antidiabetic Agent - Sulfonylureas

Storage Conditions

Store below 30°C, away from light, out of the reach of children

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