Dactus 2 mg (Tablet)

Unit Price: ৳ 7.48 (6 x 10: ৳ 448.80)
Strip Price: ৳ 74.80

Medicine Details

Category Details
Generic Glimepiride
Company Acme laboratories ltd
Also available as
Dactus 1 mg tablet Dactus 3 mg tablet

Indications

  • Lower the blood glucose in patients with noninsulin dependent (Type II) diabetes mellitus
  • Adjuvant to diet and exercise
  • Combination use with metformin
  • Combination use with insulin
  • Increase the potential for hypoglycemia

Pharmacology

  • Sulfonylurea antidiabetic agent
  • Decreases blood glucose concentration
  • Stimulates insulin release
  • Improves sensitivity of beta cells to glucose stimulus
  • Reduces basal hepatic glucose production
  • Increases peripheral tissue sensitivity to insulin

Dosage

  • Dependent on desired blood sugar level
  • Initial dose 1 mg once daily
  • Dose titration based on regular blood sugar monitoring
  • Usual dose range in well controlled diabetes 1 to 4 mg daily
  • Timing and distribution decided by physician

Administration

  • Tablet must be swallowed with sufficient liquid

Interaction

  • Potentiates hypoglycemic action with ACE inhibitors
  • Potentiates hypoglycemic action with azapropazone
  • Attenuates hypoglycemic action with barbiturates
  • Masks warning symptoms of hypoglycemic attack with beta-blockers

Contraindications

  • Not suitable for insulin dependent diabetes mellitus
  • Not suitable for diabetic ketoacidosis
  • Not suitable for diabetic coma
  • Not suitable for patients with severe hepatic dysfunction
  • Not suitable for patients with severe impairment of renal function
  • Not suitable for dialysis patients

Side Effects

  • Hypoglycemia
  • Temporary visual impairment
  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Urticaria
  • Fall in blood pressure

Pregnancy & Lactation

  • Not to be taken during pregnancy, changeover to insulin necessary
  • Ingestion with breast milk feeding may harm the child, not to be taken by breastfeeding women

Precautions & Warnings

  • Initial weeks of treatment may increase risk of hypoglycemia
  • Promptly controlled by immediate intake of carbohydrates

Overdose Effects

  • Producing hypoglycemia
  • Mild hypoglycemic symptoms should be treated aggressively
  • Severe hypoglycemic reactions constitute medical emergencies

Therapeutic Class

  • Sulfonylureas

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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