Dialon 1 mg (Tablet)

Unit Price: ৳ 6.00 (5 x 10: ৳ 300.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Glimepiride
Company Eskayef pharmaceuticals ltd
Also available as
Dialon 2 mg tablet Dialon 3 mg tablet

Indications

  • Lower blood glucose in noninsulin dependent diabetes mellitus (NIDDM) patients
  • Adjunct to diet and exercise
  • May be used concomitantly with metformin
  • Use in combination with insulin to lower blood glucose
  • Potential for hypoglycemia with combined use of Dialon and insulin

Pharmacology

  • Sulfonylurea antidiabetic agent
  • Stimulates insulin release from pancreatic beta cells
  • Improves sensitivity of beta cells to glucose stimulus
  • Reduces basal hepatic glucose production
  • Increases peripheral tissue sensitivity to insulin

Dosage

  • Initial dose of 1 mg once daily
  • Dose titration based on regular blood sugar monitoring
  • Usual dose range in well-controlled diabetes: 1 to 4 mg daily
  • Timing and distribution of doses decided by physician
  • Dose adjustment based on changes in weight or lifestyle

Administration

  • Tablet must be swallowed with sufficient amount of liquid

Interaction

  • Potentiates hypoglycemic action with certain drugs: ACE inhibitors, aminosalicylic acid, fibrates, fluconazole, etc.
  • Attenuates hypoglycemic action with certain drugs: barbiturates, corticosteroids, diazoxide, etc.
  • Beta-blockers, clonidine, and reserpine may lead to potentiation or weakening of the blood-glucose-lowering effect
  • Acute and chronic alcohol intake may affect the activity of Dialon

Contraindications

  • Not suitable for insulin-dependent diabetes mellitus
  • Not suitable for diabetic ketoacidosis or diabetic coma
  • Hypersensitivity to Glimepiride or other sulfonylureas
  • Severe hepatic dysfunction and renal impairment
  • Not for use in dialysis patients

Side Effects

  • Hypoglycemia
  • Temporary visual impairment
  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Urticaria
  • Fall in blood pressure

Pregnancy & Lactation

  • Not to be taken during pregnancy; changeover to insulin necessary
  • Breastfeeding women should not take Glimepiride

Precautions & Warnings

  • Initial weeks of treatment may increase the risk of hypoglycemia
  • Careful monitoring required
  • Prompt control of hypoglycemia by immediate intake of carbohydrates

Overdose Effects

  • Hypoglycemia
  • Mild symptoms treated with oral glucose and dosage adjustments
  • Severe reactions constitute medical emergencies
  • Rapid intravenous injection of concentrated glucose solution for hypoglycemic coma

Therapeutic Class

  • Sulfonylureas

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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