Dieta 3 mg (Tablet)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Glimepiride
Company Pacific pharmaceuticals ltd
Also available as
Dieta 1 mg tablet Dieta 2 mg tablet Dieta 4 mg tablet

Indications

  • Adjunct to diet and exercise for lowering blood glucose in noninsulin dependent diabetes mellitus (NIDDM)
  • Use in combination with metformin or insulin for adequate glycaemic control
  • Potential increase in hypoglycaemia risk with combined use of Dieta and insulin

Pharmacology

  • Sulfonylurea antidiabetic agent
  • Stimulates insulin release from pancreatic beta cells
  • Improves sensitivity of beta cells to glucose stimulus
  • Reduces basal hepatic glucose production
  • Increases peripheral tissue sensitivity to insulin
  • Hypoglycaemic action persists for 24 hours in non-fasting diabetic patients

Dosage

  • Determined by desired blood sugar level
  • Initial dose usually 1 mg once daily, with gradual increase based on blood sugar monitoring
  • Usual dose range in well controlled patients is 1 to 4 mg daily
  • Timing and distribution of doses decided by physician considering patient's lifestyle
  • Dose adjustment needed with changes in weight or lifestyle
  • Specific guidelines for changeover from other oral antidiabetics to Glimepiride

Administration

  • Tablet must be swallowed with sufficient amount of liquid

Interaction

  • Potentiating drugs include ACE inhibitors, chloramphenicol, fluoxetine, probenecid, sulphonpyrazone, tetracyclines, and more
  • Attenuating drugs include barbiturates, corticosteroids, diuretics, nicotinic acid, phenothiazines, thyroid hormones, and more
  • Possible masking of hypoglycaemic attack symptoms with certain concomitant treatments
  • Impact of alcohol intake on the activity of Dieta

Contraindications

  • Not suitable for insulin dependent diabetes mellitus or diabetic coma
  • Must not be used in patients hypersensitive to Glimepiride, other sulfonylureas, other sulfonamides, severe hepatic dysfunction, severe impairment of renal function, and dialysis patients

Side Effects

  • Hypoglycaemia
  • Temporary visual impairment
  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Urticaria
  • Fall in blood pressure

Pregnancy & Lactation

  • Not to be taken during pregnancy, requiring changeover to insulin
  • Ingestion with breastfeeding may harm the child, requiring changeover or discontinuation of breastfeeding

Precautions & Warnings

  • Increased risk of hypoglycaemia in initial weeks of treatment
  • Immediate intake of carbohydrates to control hypoglycaemia

Overdose Effects

  • Potential to produce hypoglycaemia
  • Treatment of mild hypoglycaemic symptoms with oral glucose and adjustment in dosage or meal patterns
  • Severe hypoglycaemic reactions constitute medical emergencies requiring immediate hospitalization

Therapeutic Class

  • Sulfonylureas

Storage Conditions

  • Do not store above 30°C
  • Keep away from light and out of the reach of children

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