Glimirid 3 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Glimepiride |
| Company | Aci limited |
| Also available as |
Indications
- Adjunct to diet and exercise for Type II diabetes mellitus
- Combination therapy with metformin or insulin
- Reduction of blood glucose levels
- Use in noninsulin dependent diabetes mellitus (NIDDM)
Pharmacology
- Sulfonylurea antidiabetic agent
- Decreases blood glucose concentration
- Stimulates insulin release from pancreatic beta cells
- Improves beta cell sensitivity to glucose stimulus
- Reduces basal hepatic glucose production
Dosage
- Governing dosage by desired blood sugar level
- Regular blood and urine glucose monitoring
- Initial dose of 1 mg once daily
- Dose titration based on blood sugar monitoring
- Timing and distribution of doses decided by physician
Administration
- Tablet form
- Swallowed with sufficient liquid
Interaction
- Potentiating drugs: ACE inhibitors, fluconazole, salicylates, sulphonamide antibiotics
- Attenuating drugs: Calcium channel blockers, corticosteroids, sympathomimetic agents
- Interaction with insulin and other oral antidiabetic agents
Contraindications
- Not for insulin dependent diabetes mellitus
- Not for diabetic ketoacidosis or coma
- Hypersensitivity to glimepiride or sulfonylureas
- Severe hepatic or renal dysfunction, dialysis patients
Side Effects
- Hypoglycemia
- Temporary visual impairment
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Urticaria
- Fall in blood pressure
Pregnancy & Lactation
- Not to be taken during pregnancy
- Changeover to insulin required
- Harmful during breastfeeding
Precautions & Warnings
- Initial weeks monitoring for increased hypoglycemia risk
- Immediate intake of carbohydrates for hypoglycemia control
Overdose Effects
- Hypoglycemia management with oral glucose and drug dosage adjustment
- Severe cases require hospitalization and intravenous glucose
Therapeutic Class
- Sulfonylureas
Storage Conditions
- Do not store above 30°C
- Keep away from light and out of the reach of children