Glims 1 mg (Tablet)

Unit Price: ৳ 6.00 (3 x 15: ৳ 270.00)
Strip Price: ৳ 90.00

Medicine Details

Category Details
Generic Glimepiride
Company Opsonin pharma ltd
Also available as
Glims 2 mg tablet Glims 3 mg tablet Glims 4 mg tablet

Therapeutic Class

  • Sulfonylureas

Indications

  • Adjunct to diet and exercise to lower blood glucose in noninsulin dependent diabetes mellitus
  • Used in combination with insulin to lower blood glucose
  • May be used concomitantly with metformin

Pharmacology

  • Decreases blood glucose concentration
  • Stimulates the release of insulin from pancreatic beta cells
  • Improves sensitivity of beta cells to glucose stimulus
  • Reduces basal hepatic glucose production
  • Increases peripheral tissue sensitivity to insulin
  • Hypoglycemic action persists for 24 hours in non-fasting diabetic patients

Dosage

  • Based on desired blood sugar level
  • Initial dose is 1 mg once daily
  • Usual dose range is 1 to 4 mg daily
  • Timing and distribution of doses decided by physician
  • Dose adjustment as control of diabetes improves
  • Initial daily dose is 1 mg when switching from other oral blood sugar lowering agents

Administration

Tablet must be swallowed with sufficient liquid

Interaction

  • Potentiates hypoglycemic action:
    • ACE inhibitors
    • Glucagon
    • MAO-inhibitors
    • Sulphonpyrazone
  • Attenuates hypoglycemic action:
    • Barbiturates
    • Calcium channel blockers
    • Corticosteroids

Contraindications

  • Insulin dependent diabetes mellitus
  • Diabetic ketoacidosis
  • Diabetic coma
  • Hypersensitivity to Glimepiride or sulfonylureas
  • Severe hepatic dysfunction
  • Severe impairment of renal function
  • Dialysis patients

Side Effects

  • Hypoglycemia
  • Temporary visual impairment
  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Urticaria
  • Fall in blood pressure

Pregnancy & Lactation

  • Not to be taken during pregnancy
  • Changeover to insulin necessary
  • Not to be taken by breastfeeding women

Precautions & Warnings

  • Increased risk of hypoglycemia in initial weeks of treatment
  • Monitoring required
  • Immediate intake of carbohydrates for hypoglycemia

Overdose Effects

  • Can produce hypoglycemia
  • Treat aggressively with oral glucose for mild symptoms
  • Hospitalization for severe hypoglycemic reactions

Storage Conditions

Do not store above 30°C. Keep away from light and out of the reach of children

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