Glims 2 mg (Tablet)

Unit Price: ৳ 9.00 (3 x 15: ৳ 405.00)
Strip Price: ৳ 135.00

Medicine Details

Category Details
Generic Glimepiride
Company Opsonin pharma ltd
Also available as
Glims 1 mg tablet Glims 3 mg tablet Glims 4 mg tablet

Indications

  • Adjunct to diet and exercise for lowering blood glucose in patients with Type II diabetes mellitus (NIDDM)
  • Use in combination with metformin or insulin for adequate glycaemic control
  • Increased potential for hypoglycaemia in combined use with insulin

Pharmacology

  • Sulfonylurea antidiabetic agent
  • Stimulates insulin release from pancreatic beta cells
  • Improves beta cells' sensitivity to glucose stimulus
  • Reduces basal hepatic glucose production
  • Increases peripheral tissue sensitivity to insulin

Dosage

  • Dosage based on desired blood sugar level
  • Initial dose of 1 mg once daily
  • Gradual dose titration based on blood sugar monitoring
  • Dose range of 1 to 4 mg daily in well controlled diabetes
  • Single daily dose taken before breakfast or first main meal

Administration

  • Tablet must be swallowed with sufficient amount of liquid

Interaction

  • Potentiating interactions with ACE inhibitors, aminosalicylic acid, chloramphenicol, fluoxetine, sulphonpyrazone, etc.
  • Attenuating interactions with barbiturates, corticosteroids, diuretics, nicotinic acid, etc.
  • Masking of hypoglycaemic attack symptoms by beta-receptor blockers, clonidine, etc.

Contraindications

  • Not suitable for insulin dependent diabetes mellitus or diabetic ketoacidosis
  • Hypersensitivity to Glimepiride, sulfonylureas, sulfonamides
  • Severe hepatic dysfunction, severe impairment of renal function, dialysis patients

Side Effects

  • Hypoglycaemia
  • Temporary visual impairment
  • Nausea, vomiting, diarrhoea, abdominal pain
  • Urticaria
  • Fall in blood pressure

Pregnancy & Lactation

  • Not to be taken during pregnancy, changeover to insulin necessary
  • Harmful for breastfeeding, changeover or discontinuation necessary

Precautions & Warnings

  • Increased risk of hypoglycaemia in initial treatment weeks
  • Necessitates careful monitoring and possible dosage adjustment
  • Prompt control of hypoglycaemia by immediate intake of carbohydrates

Overdose Effects

  • Hypoglycaemia from overdosage
  • Treatment with oral glucose for mild symptoms
  • Immediate hospitalization for severe hypoglycaemic reactions

Therapeutic Class

  • Sulfonylureas

Storage Conditions

  • Do not store above 30°C
  • Keep away from light and out of reach of children

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