Gluconor 2 mg (Tablet)
Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Glimepiride |
| Company | Aristopharma ltd |
| Also available as |
Indications
- Adjunct to diet and exercise for Type II diabetes mellitus
- May be used with metformin for inadequate glycaemic control
- May be used in combination with insulin for hyperglycaemia
- Potential for hypoglycaemia with combined use of Gluconor and insulin
Pharmacology
- Decreases blood glucose concentration
- Stimulates insulin release from pancreatic beta cells
- Improves sensitivity of beta cells to glucose stimulus
- Reduces basal hepatic glucose production
- Increases peripheral tissue sensitivity to insulin
- Enhances glucose uptake
Dosage
- Initial dose is 1 mg once daily
- Dose can be increased based on regular blood sugar monitoring
- Usual dose range in well controlled diabetes is 1 to 4 mg daily
- Timing and distribution of doses decided by physician
- Single daily dose sufficient, taken before substantial meal
- Dose adjustment based on changes in weight or lifestyle
Administration
- Tablet must be swallowed with sufficient amount of liquid
Interaction
- Interactions with other oral antidiabetic agents
- Drugs that may potentiate hypoglycaemic action
- Drugs that may attenuate hypoglycaemic action
- Concomitant treatment with beta-blockers, clonidine or reserpine may mask hypoglycaemic symptoms
- Alcohol intake may potentiate or attenuate activity of Gluconor
Contraindications
- Not suitable for insulin dependent diabetes mellitus
- Not suitable for diabetic ketoacidosis or diabetic coma
- Contraindicated in patients hypersensitive to Glimepiride
- Contraindicated in severe hepatic dysfunction, severe impairment of renal function, and dialysis patients
Side Effects
- Hypoglycaemia
- Temporary visual impairment
- Nausea
- Vomiting
- Diarrhoea
- Abdominal pain
- Urticaria
- Fall in blood pressure
Pregnancy & Lactation
- Not to be taken during pregnancy
- Breastfeeding is not recommended
Precautions & Warnings
- Initial weeks of treatment may increase risk of hypoglycaemia
- Carbohydrates should be taken promptly to control hypoglycaemia
Overdose Effects
- Overdosage can produce hypoglycaemia
- Mild hypoglycaemic symptoms should be treated with oral glucose and adjustments in drug dosage or meal patterns
- Severe hypoglycaemic reactions constitute medical emergencies requiring immediate hospitalization
Therapeutic Class
- Sulfonylureas
Storage Conditions
- Do not store above 30°C
- Keep away from light and out of the reach of children