Senride 1 mg (Tablet)

Unit Price: ৳ 5.75 (6 x 10: ৳ 345.00)
Strip Price: ৳ 57.50

Medicine Details

Category Details
Generic Glimepiride
Company Navana pharmaceuticals ltd
Also available as
Senride 2 mg tablet

Indications

  • Adjunct to diet and exercise for lowering blood glucose in Type II diabetes mellitus
  • May be used with metformin or insulin for glycaemic control

Pharmacology

  • Sulfonylurea antidiabetic agent
  • Stimulates insulin release from pancreatic beta cells
  • Reduces basal hepatic glucose production
  • Increases peripheral tissue sensitivity to insulin

Dosage

  • Initial dose of 1mg once daily
  • Usual dose range in well-controlled diabetes is 1 to 4mg daily
  • Timing and distribution of doses decided by physician
  • Secondary dosage adjustment based on improved diabetes control and other factors

Administration

Tablet must be swallowed with sufficient liquid

Interaction

  • Potentiating drugs:
    • ACE inhibitors
    • Azapropazone
    • Fluconazole
    • Guanethidine
    • Miconazole
    • Sulfa antibiotics
    • Tetracyclines
  • Attenuating drugs:
    • Acetazoiamide
    • Barbiturates
    • Calcium channel blockers
    • Corticosteroids
    • Diazoxide
    • Diuretics
    • Thyroid hormones
  • Masking effects:
    • Beta-blockers
    • Clonidine
    • Guanethidine
    • Reserpine
  • Alcohol intake effect: May potentiate or attenuate drug activity

Contraindications

  • Insulin-dependent diabetes mellitus
  • Diabetic ketoacidosis
  • Hypersensitivity to Glimepiride or sulfonylureas
  • Severe hepatic or renal dysfunction

Side Effects

  • Hypoglycaemia
  • Temporary visual impairment
  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Urticaria
  • Fall in blood pressure

Pregnancy & Lactation

  • Contraindicated during pregnancy
  • Changeover to insulin needed
  • Harmful during breastfeeding

Precautions & Warnings

  • Increased risk of hypoglycaemia in initial weeks of treatment
  • Immediate intake of carbohydrates for hypoglycaemia control

Overdose Effects

  • Hypoglycaemic symptoms without loss of consciousness
  • Severe hypoglycaemic reactions with coma or seizure
  • Need for aggressive treatment with oral glucose or IV injection of glucose

Therapeutic Class

Sulfonylureas

Storage Conditions

Do not store above 30°C, keep away from light and children

Related Brands