Diaplus 5 mg (Tablet)
Unit Price: ৳ 2.00 (5 x 10: ৳ 100.00)
Strip Price: ৳ 20.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Glipizide |
| Company | Pacific pharmaceuticals ltd |
| Also available as |
Indications
- Adjunct to diet for controlling hyperglycaemia
- Treatment of non-insulin-dependent diabetes mellitus
- Reduction in daily insulin dose
- Short term administration for transient control
- Maintenance of blood glucose levels
Pharmacology
- Lowers blood glucose levels
- Stimulates insulin release from pancreas
- Increases insulin sensitivity
- Decreases hepatic glucose production
Dosage & Administration
- Recommended starting dose: 5 mg before breakfast
- Initial dose for geriatric patients or those with liver disease: 2.5 mg
- Dosage adjustments based on blood glucose response
- Maximum recommended once daily dose: 15 mg
- Total daily dose range: 2.5 to 30 mg
- Conservative initial and maintenance dosing in elderly, debilitated, or malnourished patients
- Pediatric use safety and effectiveness not established
Interaction
- Potentiation of hypoglycaemic action by certain drugs
- Observation for hypoglycaemia when drugs are administered or withdrawn
- Drugs that tend to produce hyperglycaemia and affect blood glucose control
Contraindications
- Hypersensitivity to Glipizide or any component
- Juvenile onset diabetes
- Severe or unstable 'brittle' diabetes
- Diabetes complicated by ketosis and acidosis
- Severe renal, hepatic, or thyroid impairment
Side Effects
- Dose-related transient gastrointestinal complaints
- Cholestatic jaundice
- Allergic skin reactions
- Haematologic effects
- Metabolic effects
- Endocrine reactions
- Dizziness, drowsiness, and headache
Pregnancy & Lactation
- Use during pregnancy if potential benefit justifies risk
- Discontinuation one month before expected delivery date
- Avoid breastfeeding due to potential excretion in human milk
Precautions & Warnings
- Risk of severe hypoglycaemia in susceptible patients
- Caution in renal or hepatic insufficiency
- Maintenance of regular meals and appropriate calorie intake
- Potential loss of blood glucose control during stress
- Monitoring for diminished responsiveness to the drug
Therapeutic Class
- Sulfonylureas
Storage Conditions
- Store at room temperature (below 30°C)
- Protect from moisture and humidity