Bigmet 850 mg (Tablet)

Unit Price: ৳ 6.00 (10 x 10: ৳ 600.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Metformin hydrochloride
Company Renata limited
Also available as
Bigmet 500 mg tablet Bigmet xr 500 mg tablet

Title

  • Metformin Hydrochloride Tablets

Categories

  • Diabetes Management
  • Antihyperglycemic Medication

Description

  • Biguanide type oral antihyperglycemic drug
  • Used in the management of type 2 diabetes mellitus
  • Lowers both basal and postprandial plasma glucose
  • Decreases hepatic glucose production
  • Improves insulin sensitivity

Color Options

  • White

Dimensions

  • Various tablet sizes available

Dosage Form

  • Immediate release tablets
  • Extended release tablets

Dosage Administration

  • Individualized dosage based on effectiveness and tolerance
  • Maximum recommended daily doses
  • Dosage adjustments for adults and children
  • Dosage adjustments for renal impaired patients

Interaction

  • No chronic interaction information available with Furosemide
  • Potential interaction with Nifedipine and cationic drugs
  • Minimal effects on Nifedipine
  • No significant effect on Cimetidine pharmacokinetics
  • Potential drug-induced hyperglycemia leading to loss of glycemic control

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Acute metabolic acidosis
  • Severe renal failure
  • Acute conditions altering renal function
  • Conditions causing tissue hypoxia

Side Effects

  • Hemolytic anemia
  • Lactic acidosis
  • Decreased vitamin B12 absorption
  • Peripheral neuropathy
  • Taste disturbance
  • Encephalopathy
  • Gastrointestinal disorders
  • Liver function test abnormalities
  • Skin reactions

Pregnancy & Lactation

  • Uncontrolled diabetes associated with increased risk during pregnancy
  • Metformin excreted into human breast milk
  • No adverse effects observed in breastfed newborns/infants

Precautions & Warnings

  • Substantial excretion by the kidney
  • Risk of lactic acidosis
  • Lowering vitamin B12 level
  • Increased risk of hypoglycemia
  • Regular monitoring of renal function advised
  • Therapy should be stopped before surgery
  • Annual estimation of Vitamin B-12 levels
  • Interaction with anticoagulants
  • Dosage adjustments with co-administration

Use in Special Populations

  • Dosage adjustment for elderly based on renal function
  • Diagnosis confirmation before initiation in children
  • No effect on growth and puberty detected during controlled studies
  • Caution in children aged 10-12 years
  • Renal function assessment before and during treatment

Overdose Effects

  • Hypoglycemia not observed up to 85 gm doses
  • Lactic acidosis occurrence in high doses
  • Treatment in hospital
  • Hemodialysis for lactate and drug removal

Therapeutic Class

  • Biguanides

Storage Conditions

  • Recommended temperature below 30°C
  • Protected from light and moisture
  • Keep out of reach of children

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