Daomin 850 mg (Tablet)
Unit Price: ৳ 6.00 (10 x 4: ৳ 240.00)
Strip Price: ৳ 24.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Type 2 diabetes mellitus treatment
- Overweight patients management
- Dietary and exercise control
- Reduction of diabetic complications
- First-line therapy after diet failure
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers basal and postprandial plasma glucose
- Different mechanism of action from sulfonylureas
- Does not produce hypoglycemia
Dosage & Administration
- Individualized dosage based on effectiveness and tolerance
- Usual starting dose of 500 mg or 850 mg
- Dosage increases in increments of 500 mg or 850 mg
- Maximum daily doses for adults and children
- Use of Metformin immediate release and extended release tablet
- Special considerations for renal impaired patients
Interaction
- Possible interaction with Furosemide and Nifedipine
- Potential interaction with cationic drugs
- Effects on absorption and pharmacokinetics of other drugs
- Drugs causing hyperglycemia and loss of glycemic control
Contraindications
- Hypersensitivity to the active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Conditions altering renal function
- Conditions causing tissue hypoxia
- Liver or hepatic impairments
Side Effects
- Hemolytic anemia
- Lactic acidosis
- Decrease of vitamin B12 absorption
- Taste disturbance
- Gastrointestinal disorders
- Liver function test abnormalities
- Skin reactions
Pregnancy & Lactation
- Increased risk of congenital abnormalities and perinatal mortality
- Recommendation of insulin use during pregnancy
- Excretion into human breast milk
- Limited data on breastfeeding and potential adverse effects
Precautions & Warnings
- Excretion by the kidney and risk of accumulation
- Lowering of vitamin B12 level
- Increased risk of hypoglycemia in combination with insulin
- Regular monitoring of renal function
- Special precautions for elderly and pediatric population
Use in Special Populations
- Adjustment of metformin dosage in elderly subjects
- Confirmation of type 2 diabetes mellitus before treatment
- Effect on growth, puberty, and renal function in children
- Particular caution for children aged between 10 and 12 years
Overdose Effects
- Hypoglycemia with high doses
- Occurrence of lactic acidosis
- Emergency treatment in hospital
- Effectiveness of hemodialysis
Therapeutic Class
- Biguanides
Storage Conditions
- Temperature and moisture guidelines
- Protection from light
- Keep out of reach of children