Daomin XR 1000 mg (Tablet (Extended Release))
Unit Price: ৳ 9.00 (5 x 6: ৳ 270.00)
Strip Price: ৳ 54.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Treatment of type 2 diabetes mellitus in adults
- Treatment of type 2 diabetes mellitus in children from 10 years of age and adolescents
- Reduction of diabetic complications in overweight type 2 diabetic adult patients
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers both basal and postprandial plasma glucose
- Decreases hepatic glucose production
- Improves insulin sensitivity
Dosage & Administration
- Individualized dosage based on effectiveness and tolerance
- Dosage increases in increments
- Maximum recommended daily doses
- Different dosage for Metformin immediate release and extended release tablet
- Dosage for renal impaired patient
Interaction
- Interaction with Furosemide and Nifedipine
- Effects on cationic drugs and Cimetidine pharmacokinetics
- Drugs that produce hyperglycemia and lead to loss of glycemic control
Contraindications
- Hypersensitivity to the active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Acute conditions altering renal function
- Acute or chronic diseases causing tissue hypoxia
Side Effects
- Hemolytic anemia
- Lactic acidosis
- Taste disturbance
- Nausea, vomiting, diarrhea, abdominal pain
- Liver function test abnormalities
- Skin reactions
Pregnancy & Lactation
- Uncontrolled diabetes risk during pregnancy
- Metformin excretion in human breast milk
- Adverse effects on breastfed newborns/infants
Precautions & Warnings
- Excretion by the kidney
- Lower vitamin B12 level
- Increased risk of hypoglycemia
- Monitoring of renal function
- Discontinuation before surgery
- Annual estimation of Vitamin B-12 levels
- Interaction with anticoagulants
Use in Special Populations
- Elderly renal function adjustment
- Diagnosis confirmation before treatment in children
- No effect on growth and puberty detected
- Creatinine clearance determination before treatment
- Decreased renal function assessment
- Caution in situations altering renal function
Overdose Effects
- No hypoglycemia with Daomin XR doses up to 85 gm
- Lactic acidosis occurrence in high doses
- Hemodialysis for lactic acidosis removal
Therapeutic Class
- Biguanides
Storage Conditions
- Keep below 30°C
- Protected from light & moisture
- Keep out of the reach of children