Daomin XR 1000 mg (Tablet (Extended Release))

Unit Price: ৳ 9.00 (5 x 6: ৳ 270.00)
Strip Price: ৳ 54.00

Medicine Details

Category Details
Generic Metformin hydrochloride
Company Acme laboratories ltd
Also available as
Daomin 500 mg tablet Daomin 850 mg tablet Daomin xr 500 mg tablet

Indications

  • Treatment of type 2 diabetes mellitus in adults
  • Treatment of type 2 diabetes mellitus in children from 10 years of age and adolescents
  • Reduction of diabetic complications in overweight type 2 diabetic adult patients

Pharmacology

  • Biguanide type oral antihyperglycemic drug
  • Lowers both basal and postprandial plasma glucose
  • Decreases hepatic glucose production
  • Improves insulin sensitivity

Dosage & Administration

  • Individualized dosage based on effectiveness and tolerance
  • Dosage increases in increments
  • Maximum recommended daily doses
  • Different dosage for Metformin immediate release and extended release tablet
  • Dosage for renal impaired patient

Interaction

  • Interaction with Furosemide and Nifedipine
  • Effects on cationic drugs and Cimetidine pharmacokinetics
  • Drugs that produce hyperglycemia and lead to loss of glycemic control

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Acute metabolic acidosis
  • Severe renal failure
  • Acute conditions altering renal function
  • Acute or chronic diseases causing tissue hypoxia

Side Effects

  • Hemolytic anemia
  • Lactic acidosis
  • Taste disturbance
  • Nausea, vomiting, diarrhea, abdominal pain
  • Liver function test abnormalities
  • Skin reactions

Pregnancy & Lactation

  • Uncontrolled diabetes risk during pregnancy
  • Metformin excretion in human breast milk
  • Adverse effects on breastfed newborns/infants

Precautions & Warnings

  • Excretion by the kidney
  • Lower vitamin B12 level
  • Increased risk of hypoglycemia
  • Monitoring of renal function
  • Discontinuation before surgery
  • Annual estimation of Vitamin B-12 levels
  • Interaction with anticoagulants

Use in Special Populations

  • Elderly renal function adjustment
  • Diagnosis confirmation before treatment in children
  • No effect on growth and puberty detected
  • Creatinine clearance determination before treatment
  • Decreased renal function assessment
  • Caution in situations altering renal function

Overdose Effects

  • No hypoglycemia with Daomin XR doses up to 85 gm
  • Lactic acidosis occurrence in high doses
  • Hemodialysis for lactic acidosis removal

Therapeutic Class

  • Biguanides

Storage Conditions

  • Keep below 30°C
  • Protected from light & moisture
  • Keep out of the reach of children

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