Ambix 15 mg/5 ml (Syrup)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ambroxol hydrochloride |
| Company | Modern pharmaceuticals ltd |
Indications
- Productive cough
- Acute and chronic inflammatory disorders of upper and lower respiratory tracts
- Inflammatory disease of rhinopharyngeal tract
- Asthmatic bronchitis bronchial asthma
- Bronchiectasis
- Chronic pneumonia
Pharmacology
Ambroxol is the active metabolite of bromhexine, possessing a greater bronchosecretolytic effect than bromhexine. It improves sputum rheology, hydrates mechanism leading to liquefaction of mucus, stimulates production of phospholipids, reduces bronchial hyperactivity, and has anti-inflammatory properties.
Dosage & Administration
- Pediatric Drops:
- 0-6 months: 0.5 ml 2 times a day
- 6-12 months: 1 ml 2 times a day
- 1-2 years: 1.25 ml 2 times a day
- Syrup:
- 2-5 years: 2.5 ml (1/2 teaspoonful) 2-3 times a day
- 5-10 years: 5 ml (1 teaspoonful) 2-3 times a day
- 10 years and adults: 10 ml (2 teaspoonful) 3 times a day.
- Sustained release capsule: Adult and children over 12 years old: 1 capsule once daily
Interaction
Ambix should not be taken simultaneously with antitussives (e.g.Codeine) because phlegm, which has been liquefied by Ambix might not be expectorated.
Contraindications
Contraindicated in known hypersensitivity to Ambroxol or Bromhexine.
Side Effects
- Gastrointestinal side effects
- Rarely allergic responses
Pregnancy & Lactation
Teratogenic and fetal toxicity studies have shown no harmful effect of Ambroxol, but it is advised not to use it in pregnancy, especially during the 1st trimester. Safety during lactation has not been established yet.
Precautions & Warnings
Ambix should be given cautiously to patients with gastric and duodenal ulceration or convulsive disorders. Patients with hepatic and renal insufficiency should take it with caution.
Therapeutic Class
Cough expectorants & mucolytics
Storage Conditions
Protect from direct light exposure, Store in a dry place at a temperature not exceeding 30°C, Keep out of the reach of children.