Etform 500 mg (Tablet)
Unit Price: ৳ 4.00 (10 x 10: ৳ 400.00)
Strip Price: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Sandoz a novartis division |
| Also available as |
Indications
- Treatment of type 2 diabetes mellitus
- Weight management in adults and children
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers basal and postprandial plasma glucose
- Improves insulin sensitivity
Dosage & Administration
- Individualized dosage based on effectiveness and tolerance
- Immediate release and extended release tablet options
- Different dosages for adults and children
- Special precautions for renal impaired patients
Interaction
- Potential interactions with Furosemide and Nifedipine
- Competes for renal tubular transport with cationic drugs
- Impact on drugs causing hyperglycemia
Contraindications
- Hypersensitivity to the active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Acute conditions altering renal function or causing tissue hypoxia
Side Effects
- Hemolytic anemia
- Lactic acidosis
- Decrease of vitamin B12 absorption
- Peripheral neuropathy
- Taste disturbance
- Gastrointestinal disorders
- Liver function test abnormalities
- Skin reactions
Pregnancy & Lactation
- Risk of congenital abnormalities and perinatal mortality with uncontrolled diabetes during pregnancy
- Excretion into human breast milk
- Limited data on breastfeeding safety
Precautions & Warnings
- Risk of Etform accumulation and lactic acidosis with renal impairment
- Lowered vitamin B12 levels
- Increased risk of hypoglycemia
- Regular renal function monitoring
- Special caution in elderly, pediatric, and renal impaired populations
Use in Special Populations
- Dosage adjustments for elderly based on renal function
- Diagnosis confirmation before treatment in children
- Regular growth and puberty monitoring in metformin-treated children
- Creatinine clearance assessment before and during treatment
Overdose Effects
- No hypoglycemia seen with Etform doses up to 85 gm
- Lactic acidosis as medical emergency
- Hemodialysis for lactate and Etform removal
Therapeutic Class
- Biguanides
Storage Conditions
- Keep below 30°C temperature
- Protected from light and moisture
- Keep out of reach of children