Glucomin 500 mg (Tablet)
Unit Price: ৳ 4.00 (5 x 10: ৳ 200.00)
Strip Price: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Nipro jmi pharma ltd |
| Also available as |
Indications
- Treatment of type 2 diabetes mellitus
- Management of type 2 diabetes in overweight patients
- Use in adults for monotherapy
- Use in adults for combination therapy
- Use in children from 10 years of age
- Reduction of diabetic complications in overweight patients
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers basal and postprandial plasma glucose
- Decreases hepatic glucose production
- Improves insulin sensitivity
Dosage & Administration
- Usual starting dose for adults (immediate release tablet)
- Usual starting dose for children (immediate release tablet)
- Usual starting dose for adults (extended release tablet)
- Usual starting dose for children (extended release tablet)
- Maximum recommended daily doses for adults
- Maximum recommended daily doses for children
- Dosage adjustments for renal impaired patients
Interaction
- Co-administration with Furosemide
- Enhancement of absorption by Nifedipine
- Potential interactions with cationic drugs
- No effect on Cimetidine pharmacokinetics
- Drugs that produce hyperglycemia and may lead to loss of glycemic control
Contraindications
- Hypersensitivity to the active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Acute conditions altering renal function
- Acute or chronic diseases causing tissue hypoxia
Side Effects
- Hemolytic anemia
- Lactic acidosis
- Peripheral neuropathy in patients with vitamin B12 deficiency
- Taste disturbance
- Gastrointestinal disorders
- Liver function test abnormalities or hepatitis
- Skin reactions
Pregnancy & Lactation
- Increased risk of congenital abnormalities and perinatal mortality
- Excretion into human breast milk
- No adverse effects observed in breastfed newborns/infants
Precautions & Warnings
- Excretion by the kidney
- Lowering of vitamin B12 level
- Increased risk of hypoglycemia with insulin or insulin secretagogue
- Recommendation for regular monitoring of renal function
- Stopping of therapy before certain clinical investigations
- Reduction of Vitamin B-12 levels
- Consideration for blood glucose monitoring during combined therapy
- Possible interaction with anticoagulants
Use in Special Populations
- Adjustment of metformin dosage in elderly subjects
- No effect on growth and puberty in controlled clinical studies
- Particular caution in prescribing to children aged between 10 and 12 years
- Recommendation for regular assessment of renal function
- Caution in situations where renal function may become impaired
Overdose Effects
- No hypoglycemia seen at high doses
- Occurrence of lactic acidosis
- Hemodialysis as the most effective method for removal
Therapeutic Class
- Biguanides
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children