G-Metformin 500 mg (Tablet)

Unit Price: ৳ 2.50 (10 x 10: ৳ 250.00)
Strip Price: ৳ 25.00

Medicine Details

Title and Categories

  • G-Metformin Tablet
  • Diabetes Medication

Dosage Form

Immediate Release Tablet, Extended Release Tablet

Dosage Administration

  • Adult Dose: Starting from 500mg twice a day and increasing in increments
  • Children Dose: Starting from 500mg twice a day and increasing in increments
  • Dosage adjustments based on renal function
  • Maximum doses for adults and children
  • Dosage form conversion guidelines

Pharmacology

Mechanism of action, impact on glucose levels, effect on hepatic glucose production, intestinal absorption, and insulin sensitivity

Interaction

  • Effects of co-administration with Furosemide and Nifedipine
  • Potential interaction with cationic drugs and Cimetidine
  • Drugs that may induce hyperglycemia and affect glycemic control

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Acute metabolic acidosis
  • Renal failure, dehydration, severe infection, shock, and conditions causing tissue hypoxia

Side Effects

  • Blood and lymphatic system disorders
  • Metabolism and nutrition disorders
  • Nervous system disorders
  • Gastrointestinal disorders
  • Hepatobiliary disorders
  • Skin and subcutaneous tissue disorders

Pregnancy and Lactation

  • Risk of congenital abnormalities and perinatal mortality during uncontrolled diabetes
  • Excretion into breast milk and potential effects on breastfed infants

Precautions and Warnings

  • Risk of accumulation and lactic acidosis with impaired renal function
  • Impact on vitamin B12 level and risk of hypoglycemia
  • Monitoring renal function, vitamin B-12 levels, and blood glucose during therapy
  • Cautions during surgery, with sulfonylureas, cimetidine therapy, and anticoagulants

Use in Special Populations

  • Dosage adjustment for elderly subjects based on renal function
  • Effect on growth and puberty in children
  • Cautions for children aged between 10 and 12 years
  • Precautions for renal function assessment and impairment

Overdose Effects

  • Hypoglycemia and lactic acidosis
  • Treatment approach and emergency management

Therapeutic Class

Biguanides

Storage Conditions

Temperature and environmental protection

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