Informet 500 mg (Tablet)
Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Title and Category
- Informet Tablets - Type 2 Diabetes Medication
- Biguanide Antihyperglycemic Drug
Dimensions
- Tablet size: Different sizes available for immediate release tablets and extended release tablets
Color Options
- Not applicable
Functions
- Treatment of type 2 diabetes mellitus in adults, children, and adolescents
- Reduction of diabetic complications in overweight patients
- Management of basal and postprandial plasma glucose levels
- Improves insulin sensitivity
- Lowers hepatic glucose production
- Decreases intestinal absorption of glucose
- Increases peripheral glucose uptake and utilization
Materials
- Metformin Hydrochloride
Technical Specifications
- Dosage individualized based on effectiveness and tolerance
- Maximum recommended daily doses
- Metformin immediate release and extended release tablet usage details
- Use in renal impaired patients
Design Elements
- Differentiation between immediate release and extended release tablets
- Clear dosage and administration instructions
Usability Features
- Individualized dosage for adults and children
- Swallowing instructions for extended release tablet
- Renal function monitoring advice for diabetic patients
- Storage conditions for maintaining product quality
Interaction
- No chronic co-administration information with Furosemide
- Enhanced absorption with Nifedipine
- Potential interaction with cationic drugs eliminated by renal tubular secretion
- No effect on Cimetidine pharmacokinetics
- List of drugs that may produce hyperglycemia and affect glycemic control
Contraindications
- Hypersensitivity to the active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Conditions altering renal function or causing tissue hypoxia
Side Effects
- Blood and lymphatic system disorders
- Metabolism and nutrition disorders
- Nervous system disorders
- Gastrointestinal disorders
- Hepatobiliary disorders
- Skin and subcutaneous tissue disorders
Pregnancy & Lactation
- Risks of uncontrolled diabetes during pregnancy
- Recommendation for insulin use in pregnancy
- Excretion into breast milk
- Limited data on breastfeeding during metformin treatment
Precautions & Warnings
- Substantial excretion by the kidney
- Risk of lactic acidosis with impaired renal function
- Effect on vitamin B12 level
- Risk of hypoglycemia in combination with insulin
- Advised to be stopped before certain clinical investigations or after trauma
- Annual estimation of Vitamin B12 levels
- Interaction with sulphonylurea and anticoagulants
Use in Special Populations
- Adjustment of metformin dosage based on renal function in elderly subjects
- No effect on growth and puberty detected in controlled clinical studies
- Caution in children aged between 10 and 12 years
- Recommendation for regular renal function assessment
- Contraindicated in patients with GFR <30 ml/min
Overdose Effects
- Hypoglycemia not seen with doses up to 85 gm
- Occurrence of lactic acidosis in overdose circumstances
- Hemodialysis as the most effective treatment for lactic acidosis
Therapeutic Class
- Biguanides
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children