Insimet 500 mg (Tablet)
Unit Price: ৳ 4.00 (10 x 10: ৳ 400.00)
Strip Price: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Ibn sina pharmaceuticals ltd |
| Also available as |
Indications
- Type 2 diabetes mellitus treatment
- Overweight patients treatment
- Monotherapy use in adults
- Combination therapy use in adults
- Combination therapy use in children and adolescents
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers both basal and postprandial plasma glucose
- Decreases hepatic glucose production
- Improves insulin sensitivity
Dosage & Administration
- Individualized dosage based on effectiveness and tolerance
- Maximum recommended daily doses
- Starting dose for adults and children
- Dosage increases and adjustments
- Instructions for immediate release tablet
- Instructions for extended release tablet
- Dosage considerations for renal impaired patients
Interaction
- Interaction with Furosemide
- Enhancement of absorption by Nifedipine
- Potential interaction with cationic drugs
- Effects on Cimetidine pharmacokinetics
- Drugs that may produce hyperglycemia
Contraindications
- Hypersensitivity to active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Conditions altering renal function
- Conditions causing tissue hypoxia
Side Effects
- Hemolytic anemia
- Lactic acidosis
- Decrease of vitamin B12 absorption
- Peripheral neuropathy
- Taste disturbance
- Gastrointestinal disorders
- Liver function test abnormalities
- Skin reactions
Pregnancy & Lactation
- Risks during pregnancy
- Recommendation for insulin use during pregnancy
- Excretion into human breast milk
- Limited data on breastfeeding
Precautions & Warnings
- Excretion by the kidney
- Lowering of vitamin B12 level
- Increased risk of hypoglycemia
- Monitoring of renal function
- Cautions before surgery and clinical investigations
- Annual estimation of Vitamin B-12 levels
- Interaction with sulphonylurea
- Renal clearance during cimetidine therapy
- Interaction with anticoagulants
Use in Special Populations
- Dosage adjustment for elderly subjects
- Effects on growth and puberty
- Caution for children aged between 10 and 12 years
- Renal function assessment
- Caution in situations of impaired renal function
Overdose Effects
- Hypoglycemia
- Lactic acidosis
- Treatment in hospital
- Hemodialysis
Therapeutic Class
- Biguanides
Storage Conditions
- Below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children