Insimet 850 mg (Tablet)

Unit Price: ৳ 4.00 (5 x 10: ৳ 200.00)
Strip Price: ৳ 40.00

Medicine Details

Category Details
Generic Metformin hydrochloride
Company Ibn sina pharmaceuticals ltd
Also available as
Insimet 500 mg tablet Insimet xr 500 mg tablet

ProductTitle

  • Insimet Tablet

Categories

  • Medicine
  • Diabetes Management
  • Antihyperglycemic

Description

  • Used in the treatment of type 2 diabetes mellitus
  • Available in immediate release and extended release tablet forms
  • Affects basal and postprandial plasma glucose levels
  • Does not produce hypoglycemia
  • Improves insulin sensitivity
  • Decreases hepatic glucose production
  • Decreases intestinal absorption of glucose
  • Lowers vitamin B12 absorption during long-term use
  • May cause taste disturbance and gastrointestinal disorders
  • Must be stored below 30°C, protected from light & moisture, and out of the reach of children

DosageAndAdministration

  • Individualized dosage based on effectiveness and tolerance
  • Maximum daily doses for immediate release and extended release tablets
  • Dosage adjustments for adults, children from 10 years of age, and renal impaired patients

Interaction

  • Limited information on interactions with Furosemide and Nifedipine
  • Potential interaction with cationic drugs eliminated by renal tubular secretion
  • Certain drugs may lead to loss of glycemic control

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Acute metabolic acidosis, severe renal failure, and acute conditions altering renal function
  • Acute or chronic diseases causing tissue hypoxia
  • Not advised in conditions leading to dehydration or in patients with serious infections or trauma

SideEffects

  • Possible side effects on blood and lymphatic system, metabolism and nutrition, nervous system, gastrointestinal system, hepatobiliary system, and skin and subcutaneous tissue

PregnancyAndLactation

  • Not recommended during pregnancy, particularly in uncontrolled diabetes
  • Limited data available on breastfeeding while on metformin treatment

PrecautionsAndWarnings

  • Regular monitoring of renal function
  • Potential risk of hypoglycemia when used with insulin or insulin secretagogue
  • Need for vitamin B12 level estimation in continuous therapy
  • Special caution in elderly, pediatric, and renal impaired patients

UseInSpecialPopulations

  • Dosage adjustment based on renal function in elderly subjects
  • Need for confirmed diagnosis before treatment initiation in pediatric population
  • Regular follow-up recommended for children's growth and puberty, especially prepubescent children

OverdoseEffects

  • Lactic acidosis reported in overdose cases
  • Hypoglycemia not seen in Insimet doses up to 85 gm
  • Hemodialysis as the most effective method for removing lactate and Insimet

TherapeuticClass

  • Biguanides

StorageConditions

  • Keep below 30°C temperature, protected from light & moisture, and out of the reach of children

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