Meformin 850 mg (Tablet)

Unit Price: ৳ 3.01 (5 x 10: ৳ 150.50)
Strip Price: ৳ 30.10

Medicine Details

Category Details
Generic Metformin hydrochloride
Company Novatek pharmaceuticals ltd
Also available as
Meformin 500 mg tablet

Indications

  • Treatment of type 2 diabetes mellitus
  • Management of diabetes in overweight patients
  • Monotherapy for adults
  • Combination therapy for adults
  • Combination therapy for children and adolescents

Pharmacology

  • Biguanide type oral antihyperglycemic drug
  • Lowers basal and postprandial plasma glucose
  • Decreases hepatic glucose production
  • Improves insulin sensitivity
  • Decreases intestinal absorption of glucose

Dosage & Administration

  • Individualized dosage based on effectiveness and tolerance
  • Maximum recommended daily doses
  • Dosage increments for adults and children
  • Immediate release tablet dosing for adults and children
  • Extended release tablet dosing for adults

Interaction

  • Chronically co-administered with Furosemide
  • Enhances absorption of Nifedipine
  • Minimal effects on Nifedipine
  • Potential interaction with cationic drugs
  • Effects on Cimetidine pharmacokinetics

Contraindications

  • Hypersensitivity to active substances or excipients
  • Acute metabolic acidosis
  • Severe renal failure
  • Acute conditions altering renal function
  • Conditions causing tissue hypoxia

Side Effects

  • Hemolytic anemia
  • Lactic acidosis
  • Decreased vitamin B12 absorption
  • Peripheral neuropathy in patients with vitamin B12 deficiency
  • Taste disturbance
  • Encephalopathy
  • Gastrointestinal disorders
  • Liver function test abnormalities
  • Skin reactions

Pregnancy & Lactation

  • Uncontrolled diabetes risk during pregnancy
  • Recommendation for insulin use during pregnancy
  • Excretion into human breast milk
  • Limited data on breastfeeding

Precautions & Warnings

  • Substantial excretion by the kidney
  • Lower vitamin B12 level
  • Increased risk of hypoglycemia
  • Renal function monitoring
  • Pre-surgery medication adjustment
  • Caution in dehydrated conditions
  • Annual estimation of Vitamin B-12 levels
  • Hypoglycemia risk in combined therapy
  • Renal clearance during cimetidine therapy
  • Possible interaction with anticoagulants

Use in Special Populations

  • Adjusted dosage for elderly based on renal function
  • Effect on growth and puberty in children
  • Caution in prescribing to children aged 10-12 years
  • Renal function assessment before and during treatment

Overdose Effects

  • Lactic acidosis
  • Treatment with hemodialysis

Therapeutic Class

  • Biguanides

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

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