Meglu 850 mg (Tablet)
Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Unimed unihealth pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of type 2 diabetes mellitus in overweight patients
- Used as monotherapy or in combination with other oral antidiabetic agents or with insulin
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers basal and postprandial plasma glucose
- Decreases hepatic glucose production
- Improves insulin sensitivity
Dosage & Administration
- Individualized dosage based on effectiveness and tolerance
- Dosage increases should be made in increments
- Max daily doses for adults and children
- Instructions for immediate release and extended release tablets
- Cautions for renal impaired patients
Interaction
- No information available for chronic co-administration with Furosemide
- Effects of Nifedipine and Cationic drugs
- Impact on certain drugs causing hyperglycemia and loss of glycemic control
Contraindications
- Hypersensitivity to active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Acute conditions altering renal function
- Conditions causing tissue hypoxia
Side Effects
- Blood and lymphatic system disorders
- Metabolism and nutrition disorders
- Nervous system disorders
- Gastrointestinal disorders
- Hepatobiliary disorders
- Skin and subcutaneous tissue disorders
Pregnancy & Lactation
- Risk of congenital abnormalities and perinatal mortality
- Recommendation to use insulin instead of metformin during pregnancy
- Excretion into breast milk
- Potential risk to adverse effects on the child
Precautions & Warnings
- Excretion by the kidney
- Lowering of vitamin B12 level
- Increased risk of hypoglycemia when used with insulin
- Regular monitoring of renal function
- Cautions for surgery, dehydration, serious infections
- Annual estimation of Vitamin B-12 levels
- Hypoglycemia risk with combined therapy
- Interaction with cimetidine and anticoagulants
Use in Special Populations
- Dosage adjustment in elderly subjects
- Effect on growth and puberty in children
- Caution when prescribing to children aged 10-12 years
- Assessment of renal function before and during treatment
- Contraindications for GFR < 30 ml/min
Overdose Effects
- No hypoglycemia with doses up to 85 gm
- Occurrence of lactic acidosis
- Treatment with hemodialysis
Therapeutic Class
- Biguanides
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children