Met XR 500 mg (Tablet (Extended Release))
Unit Price: ৳ 6.50 (5 x 10: ৳ 325.00)
Strip Price: ৳ 65.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Opsonin pharma ltd |
| Also available as |
Title
- Met XR Tablet
Categories
- Medicine
- Diabetes Management
- Antihyperglycemic
- Biguanide
Description
- Met XR tablet is used in the treatment of type 2 diabetes mellitus, particularly in overweight patients when dietary management and exercise alone does not result in adequate glycaemic control.
DosageForm
- Immediate Release Tablet
- Extended Release Tablet
Indications
- Treatment of type 2 diabetes mellitus in overweight patients
- Reduction of diabetic complications
- Monotherapy or combination therapy in adults and children
Pharmacology
- Lowers basal and postprandial plasma glucose
- Decreases hepatic glucose production
- Improves insulin sensitivity
DosageAndAdministration
- Individualized dosage based on effectiveness and tolerance
- Usual starting dose for adults and children
- Dosage increases in increments based on response
- Renal function assessment and dose adjustment
Interaction
- Potential interaction with Furosemide and Nifedipine
- Competes for common renal tubular transport systems with cationic drugs
- Effect on drugs causing hyperglycemia
Contraindications
- Hypersensitivity to active substance or excipients
- Acute metabolic acidosis
- Severe renal or hepatic failure
- Acute conditions altering renal function
- Tissue hypoxia-inducing conditions
SideEffects
- Hemolytic anemia
- Lactic acidosis
- Vitamin B12 level decrease
- Peripheral neuropathy
- Taste disturbance
- Gastrointestinal disorders
- Liver function test abnormalities
- Skin reactions
PregnancyAndLactation
- Increased risk of congenital abnormalities and perinatal mortality with uncontrolled diabetes during pregnancy
- Not recommended during breastfeeding due to limited data available
PrecautionsAndWarnings
- Substantial excretion by the kidney
- Risk of vitamin B12 level decrease
- Increased risk of hypoglycemia when used in combination with insulin
- Regular monitoring of renal function
- Precautions in conditions causing dehydration or serious infections
SpecialPopulations
- Elderly: dosage adjustment based on renal function
- Pediatric: careful follow-up of effects
- Renal function: assessment before and during treatment
OverdoseEffects
- Lactic acidosis as a medical emergency
- Hemodialysis for removal of lactate and Met XR
TherapeuticClass
- Biguanides
StorageConditions
- Below 30°C temperature
- Protected from light and moisture
- Keep out of the reach of children
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