Metform 500 mg (Tablet)

Unit Price: ৳ 4.00 (10 x 10: ৳ 400.00)
Strip Price: ৳ 40.00

Medicine Details

Category Details
Generic Metformin hydrochloride
Company Aci limited
Also available as
Metform 850 mg tablet Metform er 500 mg tablet Metform er 1000 mg tablet

Product Title

  • Metformin Hydrochloride Tablet

Categories

  • Medicine
  • Pharmaceutical

Description

  • Used for the treatment of type 2 diabetes mellitus
  • Available in immediate release tablet and extended release tablet forms
  • Lowers both basal and postprandial plasma glucose
  • Improves insulin sensitivity and peripheral glucose uptake

Dimensions

  • Various tablet sizes available

Color Options

  • White color

Dosage

  • Dosage must be individualized based on effectiveness and tolerance
  • Available in different strengths: 500 mg, 850 mg, 1000 mg
  • Dosage increases should be made in increments
  • Recommended dosing for adults and children

Administration

  • Oral administration with meals

Mode of Action

  • Decreases hepatic glucose production
  • Decreases intestinal absorption of glucose

Interactions

  • Potential interaction with Furosemide and Nifedipine
  • Competes with cationic drugs for common renal tubular transport systems
  • Interaction with various drugs causing hyperglycemia

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Acute metabolic acidosis
  • Severe renal failure
  • Acute conditions altering renal function
  • Conditions causing tissue hypoxia

Side Effects

  • Hemolytic anemia
  • Lactic acidosis
  • Decrease of vitamin B12 absorption
  • Taste disturbance
  • Gastrointestinal disorders
  • Hepatic function test abnormalities
  • Skin reactions

Pregnancy & Lactation

  • Not recommended during pregnancy
  • Limited data available for breastfeeding

Precautions & Warnings

  • Substantial excretion by the kidney
  • Increase risk of hypoglycemia
  • Regular monitoring of renal function advised
  • Annual estimation of Vitamin B-12 levels recommended
  • Interaction with sulphonylurea leading to hypoglycemia

Use in Special Populations

  • Dosage adjustment in elderly subjects based on renal function
  • Careful follow-up of effect in children
  • Regular assessment of renal function advised

Overdose Effects

  • Lactic acidosis is a medical emergency
  • Must be treated in a hospital
  • Hemodialysis for removal of lactate and Metform

Therapeutic Class

  • Biguanides

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

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