Metform 850 mg (Tablet)

Unit Price: ৳ 6.00 (5 x 10: ৳ 300.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Metformin hydrochloride
Company Aci limited
Also available as
Metform 500 mg tablet Metform er 500 mg tablet Metform er 1000 mg tablet

Indications

  • Treatment of type 2 diabetes mellitus in adults
  • Treatment of type 2 diabetes in children and adolescents from 10 years of age
  • Reduction of diabetic complications in overweight type 2 diabetic adult patients

Pharmacology

  • Biguanide type oral antihyperglycemic drug
  • Lowers basal and postprandial plasma glucose
  • Decreases hepatic glucose production
  • Improves insulin sensitivity

Dosage & Administration

  • Individualized dosage based on effectiveness and tolerance
  • Dosage increases in increments for adults and children
  • Special dosage considerations for renal impaired patients

Interaction

  • Possible interactions with Furosemide and Nifedipine
  • Potential interaction with cationic drugs eliminated by renal tubular secretion
  • Effects on drugs that may produce hyperglycemia

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Acute metabolic acidosis
  • Severe renal failure
  • Acute conditions altering renal function
  • Conditions causing tissue hypoxia

Side Effects

  • Hemolytic anemia
  • Lactic acidosis
  • Decrease in vitamin B12 absorption
  • Peripheral neuropathy in patients with vitamin B12 deficiency
  • Taste disturbance
  • Nausea, vomiting, diarrhea, abdominal pain
  • Liver function test abnormalities or hepatitis
  • Skin reactions

Pregnancy & Lactation

  • Associations with increased risk of congenital abnormalities and perinatal mortality
  • Excretion into human breast milk
  • Recommendations for use during pregnancy and breastfeeding

Precautions & Warnings

  • Excretion by the kidney and risk of lactic acidosis
  • Decrease in vitamin B12 level
  • Increased risk of hypoglycemia when used with insulin or insulin secretagogue
  • Advice on renal function monitoring, surgery, and dehydration
  • Effects on diabetes stabilization and drug interactions

Use in Special Populations

  • Adjustment of dosage in elderly subjects based on renal function
  • Recommendations for pediatric population including age-specific precautions
  • Creatinine clearance assessment and contraindications based on renal function

Overdose Effects

  • Absence of hypoglycemia at doses up to 85 gm
  • Occurrence of lactic acidosis
  • Recommendation for hospital treatment and hemodialysis

Therapeutic Class

  • Biguanides

Storage Conditions

  • Temperature and light/moisture protection
  • Safety precautions for children

Related Brands