Metform ER 500 mg (Tablet (Extended Release))

Unit Price: ৳ 6.00 (5 x 10: ৳ 300.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Metformin hydrochloride
Company Aci limited
Also available as
Metform 500 mg tablet Metform 850 mg tablet Metform er 1000 mg tablet

Indications

  • Treatment of type 2 diabetes mellitus
  • Management of diabetes in adults and children from 10 years of age

Pharmacology

  • Biguanide type oral antihyperglycemic drug
  • Lowers both basal and postprandial plasma glucose
  • Improves insulin sensitivity

Dosage & Administration

  • Individualized dosage based on effectiveness and tolerance
  • Maximum recommended daily doses
  • Instructions for immediate and extended-release tablets
  • Dosage adjustments for renal impaired patients

Interaction

  • Potential interactions with other medications
  • Effects on absorption of specific drugs
  • Drugs that may lead to loss of glycemic control

Contraindications

  • Hypersensitivity to active substance or excipients
  • Acute metabolic acidosis
  • Severe renal failure
  • Acute conditions altering renal function

Side Effects

  • Hemolytic anemia
  • Lactic acidosis
  • Decrease of vitamin B12 absorption
  • Peripheral neuropathy
  • Taste disturbance
  • Gastrointestinal disorders
  • Liver function test abnormalities
  • Skin reactions

Pregnancy & Lactation

  • Increased risk of congenital abnormalities and perinatal mortality with uncontrolled diabetes
  • Excretion into human breast milk
  • Recommendation against breastfeeding during treatment

Precautions & Warnings

  • Excretion by the kidney
  • Potential for lactic acidosis
  • Lowering of vitamin B12 level
  • Increased risk of hypoglycemia
  • Recommendations for surgery and clinical investigations
  • Monitoring of renal function
  • Stabilization of diabetic patients with insulin
  • Reduced renal clearance during cimetidine therapy
  • Interaction with anticoagulants

Use in Special Populations

  • Dosage adjustment for elderly subjects based on renal function
  • No effect on growth and puberty in controlled clinical studies
  • Recommendations for pediatric use
  • Assessment of renal function and creatinine clearance

Overdose Effects

  • Risk of lactic acidosis and hypoglycemia in overdose situations
  • Treatment with hemodialysis

Therapeutic Class

  • Biguanides

Storage Conditions

  • Temperature and moisture requirements
  • Protection from light
  • Keep out of the reach of children

Related Brands