Metlife 500 mg (Tablet)
Unit Price: ৳ 3.01 (10 x 10: ৳ 301.00)
Strip Price: ৳ 30.10
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Silva pharmaceuticals ltd |
| Also available as |
Title
- Metlife - Metformin Hydrochloride Tablet
Categories
- Medicine
- Diabetes Management
- Oral Antidiabetic
Description
- Metlife is a biguanide type oral antihyperglycemic drug used in the management of type 2 diabetes mellitus. It lowers both basal and postprandial plasma glucose.
- Metlife is indicated for the treatment of type 2 diabetes mellitus, particularly in overweight patients when dietary management and exercise alone does not result in adequate glycemic control.
- Metlife is available in immediate release and extended release tablet forms.
Color Options
- White
Dimensions
- Various dimensions based on dosage strength and tablet form
Mode of Action
- Lowers both basal and postprandial plasma glucose
- Decreases hepatic glucose production
- Decreases intestinal absorption of glucose
- Improves insulin sensitivity by increasing peripheral glucose uptake and utilization
Dosage & Administration
- The dosage of Metformin Hydrochloride must be individualized on the basis of both effectiveness and tolerance, while not exceeding the maximum recommended daily doses
- Usual starting doses and titration for adults and children
- Dosage adjustments based on renal function
- Instructions for swallowing extended release tablet whole and not crushing, cutting, or chewing
Interactions
- Possible interactions with certain drugs affecting renal tubular secretion
- Effects on Cationic drugs like Amiloride, Digoxin, and others
- Cautions with drugs that may produce hyperglycemia
Contraindications
- Hypersensitivity to the active substance or to any of the excipients
- Acute metabolic acidosis, severe renal failure, acute conditions altering renal function, and conditions causing tissue hypoxia
Side Effects
- Blood and lymphatic system disorders
- Metabolism and nutrition disorders
- Nervous system disorders
- Gastrointestinal disorders
- Hepatobiliary disorders
- Skin and subcutaneous tissue disorders
Pregnancy & Lactation
- Uncontrolled diabetes during pregnancy is associated with an increased risk of congenital abnormalities and perinatal mortality
- Excretion of Metformin into human breast milk
- Recommendations for the use of insulin during pregnancy and lactation
Precautions & Warnings
- Risk of Metformin accumulation and lactic acidosis with impaired renal function
- Lowering of vitamin B12 levels
- Increased risk of hypoglycemia with insulin or insulin secretagogue
- Regular monitoring of renal function
- Cautions with surgeries, dehydration, serious infections, trauma, and other conditions
Use in Special Populations
- Adjustment of metformin dosage based on renal function in elderly subjects
- Diagnostic confirmation before initiating treatment in children
- Renal function assessment before treatment initiation and regularly thereafter
- Cautions with specific age groups and renal functions
Overdose Effects
- Hypoglycemia and lactic acidosis in overdose situations
- Treatment of lactic acidosis as a medical emergency
Therapeutic Class
- Biguanides
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children