Metmin 850 mg (Tablet)

Unit Price: ৳ 5.50 (10 x 10: ৳ 550.00)
Strip Price: ৳ 55.00

Medicine Details

Category Details
Generic Metformin hydrochloride
Company Alco pharma ltd
Also available as
Metmin xr 500 mg tablet Metmin 500 mg tablet

Indications

  • Type 2 diabetes mellitus treatment
  • Management of type 2 diabetes in overweight patients
  • Monotherapy for adults with diabetes
  • Combination therapy for adults and children with diabetes
  • Reduction of diabetic complications in overweight adults

Pharmacology

  • Biguanide type oral antihyperglycemic drug
  • Lowers basal and postprandial plasma glucose
  • Different mechanism of action from sulfonylureas
  • Does not produce hypoglycemia
  • Decreases hepatic glucose production
  • Improves insulin sensitivity

Dosage & Administration

  • Individualized dosage based on effectiveness and tolerance
  • Usual starting dose of 500mg or 850mg
  • Dosage increases in increments of 500mg or 850mg
  • Maximum recommended daily doses
  • Dosage for immediate release and extended release tablets
  • Renal impaired patient dosage precautions

Interaction

  • No information available about specific drug interactions
  • Potential interactions with cationic drugs
  • Certain drugs may produce hyperglycemia
  • Possible interaction with cimetidine
  • Potential effects on renal tubular transport systems

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Acute metabolic acidosis
  • Severe renal failure
  • Conditions altering renal function
  • Conditions causing tissue hypoxia

Side Effects

  • Hemolytic anemia
  • Lactic acidosis
  • Decrease of vitamin B12 absorption
  • Peripheral neuropathy in patients with vitamin B12 deficiency
  • Taste disturbance
  • Encephalopathy
  • Gastrointestinal disorders
  • Liver function abnormalities
  • Skin reactions

Pregnancy & Lactation

  • Management recommendations during pregnancy
  • Excretion into human breast milk
  • Limited data on breastfeeding effects

Precautions & Warnings

  • Risk of lactic acidosis with impaired renal function
  • Lowering of vitamin B12 levels
  • Increased risk of hypoglycemia
  • Regular monitoring of renal function
  • Advisory for surgery and clinical investigations
  • Discontinuation in conditions causing dehydration

Use in Special Populations

  • Elderly renal function assessment
  • Effect on growth and puberty
  • Caution in prescribing to children
  • Evaluation of renal function before treatment

Overdose Effects

  • No hypoglycemia observed at high doses
  • Possibility of lactic acidosis
  • Hemodialysis as treatment method

Therapeutic Class

  • Biguanides

Storage Conditions

  • Keep below 30°C temperature
  • Protection from light and moisture
  • Keep out of reach of children

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