Metmin 850 mg (Tablet)
Unit Price: ৳ 5.50 (10 x 10: ৳ 550.00)
Strip Price: ৳ 55.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Alco pharma ltd |
| Also available as |
Indications
- Type 2 diabetes mellitus treatment
- Management of type 2 diabetes in overweight patients
- Monotherapy for adults with diabetes
- Combination therapy for adults and children with diabetes
- Reduction of diabetic complications in overweight adults
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers basal and postprandial plasma glucose
- Different mechanism of action from sulfonylureas
- Does not produce hypoglycemia
- Decreases hepatic glucose production
- Improves insulin sensitivity
Dosage & Administration
- Individualized dosage based on effectiveness and tolerance
- Usual starting dose of 500mg or 850mg
- Dosage increases in increments of 500mg or 850mg
- Maximum recommended daily doses
- Dosage for immediate release and extended release tablets
- Renal impaired patient dosage precautions
Interaction
- No information available about specific drug interactions
- Potential interactions with cationic drugs
- Certain drugs may produce hyperglycemia
- Possible interaction with cimetidine
- Potential effects on renal tubular transport systems
Contraindications
- Hypersensitivity to the active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Conditions altering renal function
- Conditions causing tissue hypoxia
Side Effects
- Hemolytic anemia
- Lactic acidosis
- Decrease of vitamin B12 absorption
- Peripheral neuropathy in patients with vitamin B12 deficiency
- Taste disturbance
- Encephalopathy
- Gastrointestinal disorders
- Liver function abnormalities
- Skin reactions
Pregnancy & Lactation
- Management recommendations during pregnancy
- Excretion into human breast milk
- Limited data on breastfeeding effects
Precautions & Warnings
- Risk of lactic acidosis with impaired renal function
- Lowering of vitamin B12 levels
- Increased risk of hypoglycemia
- Regular monitoring of renal function
- Advisory for surgery and clinical investigations
- Discontinuation in conditions causing dehydration
Use in Special Populations
- Elderly renal function assessment
- Effect on growth and puberty
- Caution in prescribing to children
- Evaluation of renal function before treatment
Overdose Effects
- No hypoglycemia observed at high doses
- Possibility of lactic acidosis
- Hemodialysis as treatment method
Therapeutic Class
- Biguanides
Storage Conditions
- Keep below 30°C temperature
- Protection from light and moisture
- Keep out of reach of children