Metnil 500 mg (Tablet)

Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00

Medicine Details

Category Details
Generic Metformin hydrochloride
Company Medicon pharmaceuticals ltd

Title

  • Metnil - Metformin Hydrochloride Tablet

Categories

  • Diabetes Care
  • Oral Antihyperglycemic Drugs
  • Biguanides

Description

  • Treatment of type 2 diabetes mellitus in adults and children from 10 years of age
  • Oral antidiabetic therapy for overweight patients
  • Pharmacological management of type 2 diabetes
  • Dosage and administration instructions for immediate release and extended release tablets
  • Drug interactions with other medications such as Furosemide, Nifedipine, Cimetidine, etc.
  • Contraindications for specific medical conditions and acute metabolic issues
  • Possible side effects on blood, lymphatic system, metabolism, nervous system, gastrointestinal system, and skin
  • Guidelines for usage during pregnancy, lactation, in elderly patients, and special populations like children
  • Precautions, warnings, and potential risks such as renal impairment, vitamin B12 level, and hypoglycemia
  • Overdose effects and emergency treatment for lactic acidosis
  • Therapeutic classification in the category of Biguanides
  • Storage conditions to maintain temperature, light, and moisture

Dimensions

  • Tablet Size: 500mg, 850mg, 1000mg
  • Packaging: Bottle, Blister Pack

Color Options

  • White
  • Off-white

Functions

  • Glycaemic Control: Lowers both basal and postprandial plasma glucose
  • Insulin Sensitivity: Improves insulin sensitivity by increasing peripheral glucose uptake and utilization

Dosage

  • Immediate Release Tablet - Adult: Starting dose: 500mg twice a day or 850mg once a day, with meal
  • Immediate Release Tablet - Children: Starting dose: 500mg twice a day, with meal
  • Extended Release Tablet - Adult: Starting dose: 500mg once daily with evening meal
  • Extended Release Tablet - Children: Not studied
  • Renal Impaired Patient: Avoid usage in patients with eGFR below 30 mL/min/1.73 m^2

Drug Interactions

  • Furosemide
  • Nifedipine
  • Cimetidine
  • Cationic drugs (Amiloride, Digoxin, Morphine, etc.)
  • Thiazides, diuretics, corticosteroids, etc.

Contraindications

  • Hypersensitivity to active substance or excipients
  • Acute metabolic acidosis
  • Severe renal failure
  • Conditions altering renal or tissue function
  • Acute or chronic diseases affecting organ function

Side Effects

  • Hemolytic Anemia
  • Lactic Acidosis
  • Decrease of Vitamin B12 absorption
  • Peripheral Neuropathy
  • Taste Disturbance
  • Gastrointestinal Disorders
  • Liver Function Test Abnormalities
  • Skin Reactions

Pregnancy & Lactation

  • Uncontrolled diabetes risk during pregnancy
  • Potential excretion into human breast milk
  • Limited data on breastfeeding effects

Precautions & Warnings

  • Excretion by kidney and risk of accumulation
  • Lowering of Vitamin B12 level
  • Potential hypoglycemia risk with insulin usage
  • Regular monitoring of renal function
  • Caution in elderly subjects and children
  • Special care in conditions causing dehydration or infections

Use in Special Populations

  • Adjusted dosage for elderly with renal function concerns
  • Confirmation of type 2 diabetes before treatment in children
  • Monitoring of growth and puberty effects in metformin-treated children
  • Evaluation of renal function in various patient categories

Overdose Effects

  • Hypoglycemia
  • Lactic Acidosis
  • Emergency treatment with hemodialysis

Therapeutic Class

Biguanides

Storage Conditions

Temperature below 30°C, protected from light and moisture

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