Metomin 850 mg (Tablet)
Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Somatec pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of type 2 diabetes mellitus
- Management of type 2 diabetes in overweight patients
- Adults: monotherapy or combination therapy
- Children: monotherapy or combination therapy
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers basal and postprandial plasma glucose
- Different mechanism of action from sulfonylureas
- Does not produce hypoglycemia
- Decreases hepatic glucose production
- Decreases intestinal absorption of glucose
- Improves insulin sensitivity
Dosage & Administration
- Immediate release tablet: individualized dosage
- Adults: starting dose, dosage increases, maximum dose
- Children: starting dose, maximum dose
- Extended release tablet: swallow whole, dosage instructions for adults
- Renal impaired patient: usage restrictions
Interaction
- Interactions with Furosemide and Nifedipine
- Potential interaction with cationic drugs
- No effect on Cimetidine pharmacokinetics
- Hyperglycemia-inducing drugs
- Drugs affecting renal tubular transport
Contraindications
- Hypersensitivity to active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Acute conditions altering renal function
- Conditions causing tissue hypoxia
Side Effects
- Blood and lymphatic system disorders
- Metabolism and nutrition disorders
- Nervous system disorders
- Gastrointestinal disorders
- Hepatobiliary disorders
- Skin and subcutaneous tissue disorders
Pregnancy & Lactation
- Risks associated with uncontrolled diabetes during pregnancy
- Recommendation to use insulin during pregnancy
- Excretion into human breast milk
- Breastfeeding not recommended during treatment
Precautions & Warnings
- Excretion by the kidney
- Risk of lactic acidosis
- Lowering of vitamin B12 level
- Increased risk of hypoglycemia
- Monitoring of renal function
- Surgery and clinical investigations precautions
Use in Special Populations
- Elderly: dosage adjustment based on renal function
- Pediatric population: diagnosis confirmation required
- Renal function assessment and monitoring
- Caution in renal function-impaired situations
Overdose Effects
- Hypoglycemia risk
- Lactic acidosis risk
- Emergency treatment in hospital
- Hemodialysis for lactate and metformin removal
Therapeutic Class
- Biguanides
Storage Conditions
- Keep below 30°C
- Protected from light and moisture
- Keep out of the reach of children