Metsa 850 mg (Tablet)

Unit Price: ৳ 5.02 (5 x 10: ৳ 251.00)
Strip Price: ৳ 50.20

Medicine Details

Category Details
Generic Metformin hydrochloride
Company Synovia pharma plc
Also available as
Metsa 500 mg tablet Metsa xr 500 mg tablet Metsa xr 1000 mg tablet Metsa xr 750 mg tablet

Indications

  • Treatment of type 2 diabetes mellitus
  • Management of overweight patients with inadequate glycaemic control
  • Reduction of diabetic complications in adults
  • Treatment for children from 10 years of age and adolescents

Pharmacology

  • Biguanide type oral antihyperglycemic drug
  • Lowers basal and postprandial plasma glucose
  • Decreases hepatic glucose production
  • Improves insulin sensitivity

Dosage & Administration

  • Dosage individualized based on effectiveness and tolerance
  • Usual starting dose for adults is 500 mg twice a day
  • Dosage increases made in increments of 500 mg weekly
  • Renal impaired patient precautions

Interaction

  • No chronic co-administration information available
  • Enhanced absorption with Nifedipine
  • Potential interactions with cationic drugs
  • Certain drugs may lead to loss of glycemic control

Contraindications

  • Hypersensitivity to active substance or excipients
  • Acute metabolic acidosis
  • Severe renal failure
  • Acute conditions altering renal function
  • Conditions causing tissue hypoxia

Side Effects

  • Hemolytic anemia
  • Lactic acidosis
  • Decreased vitamin B12 absorption
  • Peripheral neuropathy
  • Taste disturbance
  • Gastrointestinal disorders
  • Liver function test abnormalities
  • Skin reactions

Pregnancy & Lactation

  • Uncontrolled diabetes risk during pregnancy
  • Recommendation to use insulin during pregnancy
  • Excretion into breast milk
  • No adverse effects observed in breastfed infants

Precautions & Warnings

  • Substantial excretion by the kidney
  • Lowered vitamin B12 level
  • Risk of hypoglycemia
  • Monitoring of renal function advised
  • Discontinued 2-3 days before certain procedures

Use in Special Populations

  • Elderly dosage adjustment based on renal function
  • Diagnosis confirmation in pediatric population
  • Regular assessment of renal function necessary
  • Particular caution in children aged 10-12 years

Overdose Effects

  • Hypoglycemia not seen at doses up to 85 gm
  • Lactic acidosis
  • Hemodialysis for lactic acidosis treatment

Therapeutic Class

  • Biguanides

Storage Conditions

  • Temperature below 30°C
  • Protected from light & moisture
  • Keep out of the reach of children

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